TY - JOUR
T1 - Heterobimetallic Ru(II)-Eu(III) Complex as Chemodosimeter for Selective Biogenic Amine Odorants Detection in Fish Sample
AU - Chow, Cheuk-Fai
AU - Kong, Hoi-Kuan
AU - Leung, Shu-Wai
AU - Chiu, Brenda K. W.
AU - Koo, Chi-Kin
AU - Lei, Elva N. Y.
AU - Lam, Michael H. W.
AU - Wong, Wing-Tak
AU - Wong, Wai-Yeung
PY - 2011/1/1
Y1 - 2011/1/1
N2 - Gaseous biogenic amines such as putrescine, spermidine, aniline, and trimethylamine are important biomolecules that play many crucial roles in metabolism and medical diagnostics. A chemodosimetric detection assay has been developed for those gaseous amines by RuII-EuIII heterobimetallic complexes, K{[RuII(tBubpy)(CN) 4]2EuIII(H2O)4} (where tBubpy = 4,4′-di-tert-butyl-2,2′-bipyridine). Synthesis, X-ray crystal characterization, and spectroscopic properties of this RuII-EuIII heterobimetallic complex were reported. Binding properties of the RuII-EuIII complex with common gases revealed that this complex is very selective to gaseous amine molecules. Sensitivity of this complex toward the amines was found as ∼log k = 4.5-4.8. Real time monitoring of gaseous biogenic amines was applied to real fish samples (Atlantic mackerel) by studying the spectrofluorimetric responses of the RuII-EuIII complex toward different biogenic amine concentration. GC/MS studies were also used as a reference for the studies. A linear spectrofluorimetric response was found toward biogenic amine concentration in real fish samples. This complex was found to respond specifically to those biogenic amines down to 10 ppb.
AB - Gaseous biogenic amines such as putrescine, spermidine, aniline, and trimethylamine are important biomolecules that play many crucial roles in metabolism and medical diagnostics. A chemodosimetric detection assay has been developed for those gaseous amines by RuII-EuIII heterobimetallic complexes, K{[RuII(tBubpy)(CN) 4]2EuIII(H2O)4} (where tBubpy = 4,4′-di-tert-butyl-2,2′-bipyridine). Synthesis, X-ray crystal characterization, and spectroscopic properties of this RuII-EuIII heterobimetallic complex were reported. Binding properties of the RuII-EuIII complex with common gases revealed that this complex is very selective to gaseous amine molecules. Sensitivity of this complex toward the amines was found as ∼log k = 4.5-4.8. Real time monitoring of gaseous biogenic amines was applied to real fish samples (Atlantic mackerel) by studying the spectrofluorimetric responses of the RuII-EuIII complex toward different biogenic amine concentration. GC/MS studies were also used as a reference for the studies. A linear spectrofluorimetric response was found toward biogenic amine concentration in real fish samples. This complex was found to respond specifically to those biogenic amines down to 10 ppb.
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UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-78650797102&origin=recordpage
U2 - 10.1021/ac102393f
DO - 10.1021/ac102393f
M3 - RGC 21 - Publication in refereed journal
C2 - 21138296
SN - 0003-2700
VL - 83
SP - 289
EP - 296
JO - Analytical Chemistry
JF - Analytical Chemistry
IS - 1
ER -