Hemocompatibility and antibacterial properties of lanthanum oxide films synthesized by dual plasma deposition

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • F. J. Jing
  • N. Huang
  • Y. W. Liu
  • X. B. Zhao
  • R. K Y Fu
  • J. B. Wang
  • Z. Y. Shao
  • J. Y. Chen
  • Y. X. Leng
  • X. Y. Liu

Detail(s)

Original languageEnglish
Pages (from-to)1027-1033
Journal / PublicationJournal of Biomedical Materials Research - Part A
Volume87
Issue number4
Publication statusPublished - 15 Dec 2008

Abstract

Lanthanum oxide (La2O3) films with good hemocompatibility and antibacterial properties have been fabricated using dual plasma deposition. X-ray photoelectron spectroscopy (XPS) shows that La exists in the +3 oxidation state. The band gap of the materials is determined to be 3.6 eV. Activated partial thromboplastin time (APTT) and blood platelet adhesion tests were used to evaluate the blood compatibility. The bacteria, Staphylococcus aureus, were used in plate counting tests to determine the surface antibacterial properties. The APTT is a little longer than those of blood plasma and stainless steel (SS). Furthermore, the numbers of adhered, aggregated, and morphologically changed platelets are reduced compared with those on low-temperature isotropic carbon and SS. The antibacterial plate-counting test indicates that La2O3 has good antibacterial activity against S. aureus. These unique hemocompatibility and antibacterial properties make La2O3 useful in many biomedical applications. © 2008 Wiley Periodicals, Inc.

Research Area(s)

  • Antibacterial properties, Blood compatibility, Dual plasma deposition, Lanthanum oxide

Citation Format(s)

Hemocompatibility and antibacterial properties of lanthanum oxide films synthesized by dual plasma deposition. / Jing, F. J.; Huang, N.; Liu, Y. W.; Zhang, W.; Zhao, X. B.; Fu, R. K Y; Wang, J. B.; Shao, Z. Y.; Chen, J. Y.; Leng, Y. X.; Liu, X. Y.; Chu, P. K.

In: Journal of Biomedical Materials Research - Part A, Vol. 87, No. 4, 15.12.2008, p. 1027-1033.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review