Grand challenges in bioengineered nanorobotics for cancer therapy

Scott C. Lenaghan, Yongzhong Wang, Ning Xi, Toshio Fukuda, Tzyhjong Tarn, William R. Hamel, Mingjun Zhang

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    56 Citations (Scopus)

    Abstract

    One of the grand challenges currently facing engineering, life sciences, and medicine is the development of fully functional nanorobots capable of sensing, decision making, and actuation. These nanorobots may aid in cancer therapy, site-specific drug delivery, circulating diagnostics, advanced surgery, and tissue repair. In this paper, we will discuss, from a bioinspired perspective, the challenges currently facing nanorobotics, including core design, propulsion and power generation, sensing, actuation, control, decision making, and system integration. Using strategies inspired from microorganisms, we will discuss a potential bioengineered nanorobot for cancer therapy. © 2013 IEEE.
    Original languageEnglish
    Pages (from-to)667-673
    JournalIEEE Transactions on Biomedical Engineering
    Volume60
    Issue number3
    Online published1 Feb 2013
    DOIs
    Publication statusPublished - Mar 2013

    Research Keywords

    • Bioengineered robots
    • Cancer therapy
    • Medical robotics
    • Micro/nano-robotics
    • Nanobiotechnology
    • Nanoparticles

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