Gold nanoparticle decorated flexible carbon cloth for sensitive detection of 2, 6-pyridine dicarboxylic acid by surface-enhanced Raman scattering

Lin CHEN; Dong YANG; Xianglong BIAN; Qianfeng XIA; Paul K CHU; Tingwei HU

doi:10.1364/BOE.562344

Gold nanoparticle decorated flexible carbon cloth for sensitive detection of 2, 6-pyridine dicarboxylic acid by surface-enhanced Raman scattering

Lin CHEN (Co-first Author), Dong YANG (Co-first Author), Xianglong BIAN, Qianfeng XIA, Paul K CHU, Tingwei HU^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

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Abstract

The lethal bacterium of bacillus anthracis has been recognized as a kind of formidable biological warfare agent, and the biomarker of 2, 6-pyridine dicarboxylic acid (DPA) is a crucial component of the protective layer of anthrax spore. The development of an efficient and sensitive detection method for DPA is necessary to prevent the potential biological threats. In this experiment, the porous carbon cloth (CC) and different sizes of gold nanoparticles (AuNPs) are composited together to construct a flexible SERS substrate of AuNPs@Au/CC. The high surface-enhanced Raman scattering (SERS) performance of AuNPs@Au/CC substrate is assessed by the probe molecule of Rhodamine 6 G (R6 G). During the detection of DPA, the SERS substrate of AuNPs@Au/CC exhibits a linear detection range from 10⁻⁷ M to 10⁻¹³ M with a limit of detection (LOD) of 1.58 × 10⁻¹³ M. The flexible CC substrate decorated with different sizes of AuNPs can facilitate the contact of DPA molecules and enhance the Raman signal. It provides potential application for the rapid and sensitive DPA detection for preventing the biological threats. © 2025 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement.

Original language	English
Pages (from-to)	2198-2209
Journal	Biomedical Optics Express
Volume	16
Issue number	5
Online published	1 May 2025
DOIs	https://doi.org/10.1364/BOE.562344
Publication status	Published - 1 May 2025

Funding

Natural Science Foundation of Hainan Province (521RC555).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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COPYRIGHT TERMS OF DEPOSITED FINAL PUBLISHED VERSION FILE: © 2025 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for noncommercial purposes and appropriate attribution is maintained. All other rights are reserved.

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title = "Gold nanoparticle decorated flexible carbon cloth for sensitive detection of 2, 6-pyridine dicarboxylic acid by surface-enhanced Raman scattering",

abstract = "The lethal bacterium of bacillus anthracis has been recognized as a kind of formidable biological warfare agent, and the biomarker of 2, 6-pyridine dicarboxylic acid (DPA) is a crucial component of the protective layer of anthrax spore. The development of an efficient and sensitive detection method for DPA is necessary to prevent the potential biological threats. In this experiment, the porous carbon cloth (CC) and different sizes of gold nanoparticles (AuNPs) are composited together to construct a flexible SERS substrate of AuNPs@Au/CC. The high surface-enhanced Raman scattering (SERS) performance of AuNPs@Au/CC substrate is assessed by the probe molecule of Rhodamine 6 G (R6 G). During the detection of DPA, the SERS substrate of AuNPs@Au/CC exhibits a linear detection range from 10−7 M to 10−13 M with a limit of detection (LOD) of 1.58 × 10−13 M. The flexible CC substrate decorated with different sizes of AuNPs can facilitate the contact of DPA molecules and enhance the Raman signal. It provides potential application for the rapid and sensitive DPA detection for preventing the biological threats. {\textcopyright} 2025 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement.",

author = "Lin CHEN and Dong YANG and Xianglong BIAN and Qianfeng XIA and CHU, {Paul K} and Tingwei HU",

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language = "English",

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journal = "Biomedical Optics Express",

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Gold nanoparticle decorated flexible carbon cloth for sensitive detection of 2, 6-pyridine dicarboxylic acid by surface-enhanced Raman scattering. / CHEN, Lin (Co-first Author); YANG, Dong (Co-first Author); BIAN, Xianglong et al.
In: Biomedical Optics Express, Vol. 16, No. 5, 01.05.2025, p. 2198-2209.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

TY - JOUR

T1 - Gold nanoparticle decorated flexible carbon cloth for sensitive detection of 2, 6-pyridine dicarboxylic acid by surface-enhanced Raman scattering

AU - CHEN, Lin

AU - YANG, Dong

AU - BIAN, Xianglong

AU - XIA, Qianfeng

AU - CHU, Paul K

AU - HU, Tingwei

PY - 2025/5/1

Y1 - 2025/5/1

N2 - The lethal bacterium of bacillus anthracis has been recognized as a kind of formidable biological warfare agent, and the biomarker of 2, 6-pyridine dicarboxylic acid (DPA) is a crucial component of the protective layer of anthrax spore. The development of an efficient and sensitive detection method for DPA is necessary to prevent the potential biological threats. In this experiment, the porous carbon cloth (CC) and different sizes of gold nanoparticles (AuNPs) are composited together to construct a flexible SERS substrate of AuNPs@Au/CC. The high surface-enhanced Raman scattering (SERS) performance of AuNPs@Au/CC substrate is assessed by the probe molecule of Rhodamine 6 G (R6 G). During the detection of DPA, the SERS substrate of AuNPs@Au/CC exhibits a linear detection range from 10−7 M to 10−13 M with a limit of detection (LOD) of 1.58 × 10−13 M. The flexible CC substrate decorated with different sizes of AuNPs can facilitate the contact of DPA molecules and enhance the Raman signal. It provides potential application for the rapid and sensitive DPA detection for preventing the biological threats. © 2025 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement.

AB - The lethal bacterium of bacillus anthracis has been recognized as a kind of formidable biological warfare agent, and the biomarker of 2, 6-pyridine dicarboxylic acid (DPA) is a crucial component of the protective layer of anthrax spore. The development of an efficient and sensitive detection method for DPA is necessary to prevent the potential biological threats. In this experiment, the porous carbon cloth (CC) and different sizes of gold nanoparticles (AuNPs) are composited together to construct a flexible SERS substrate of AuNPs@Au/CC. The high surface-enhanced Raman scattering (SERS) performance of AuNPs@Au/CC substrate is assessed by the probe molecule of Rhodamine 6 G (R6 G). During the detection of DPA, the SERS substrate of AuNPs@Au/CC exhibits a linear detection range from 10−7 M to 10−13 M with a limit of detection (LOD) of 1.58 × 10−13 M. The flexible CC substrate decorated with different sizes of AuNPs can facilitate the contact of DPA molecules and enhance the Raman signal. It provides potential application for the rapid and sensitive DPA detection for preventing the biological threats. © 2025 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement.

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Gold nanoparticle decorated flexible carbon cloth for sensitive detection of 2, 6-pyridine dicarboxylic acid by surface-enhanced Raman scattering

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