Glucose oxidase immobilization platform based on ZnO nanowires supported by silicon nanowires for glucose biosensing

A nanostructured platform composed of ZnO nanowires supported by silicon nanowires (ZnO/SiNWs) is utilized to immobilize glucose oxidase on a glucose enzymatic biosensor. The SiNWs arrays are fabricated by a simple metal-catalyzed solution method under normal conditions and ZnO nanowires about 650 nm long are produced on the wall of the silicon nanowires by aqueous thermal decomposition. The large specific surface area, abundant microspace, small channels, and high isoelectric point (IEP) fracture of ZnO enable effective fluid circulation and good biocompatibility boding well for immobilization of enzymes. The nanocomposite materials show good electrocatalytic activity exhibiting strong and sensitive response to glucose even in the presence of high concentrations of interfering species besides excellent long-term stability and reproducibility.