Genetic characterization of Mycobacterium avium isolates recovered from humans and animals in Australia

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • M. M. Feizabadi
  • I. D. Robertson
  • D. V. Cousins
  • D. Dawson
  • W. Chew
  • G. L. Gilbert

Detail(s)

Original languageEnglish
Pages (from-to)41-49
Journal / PublicationEpidemiology and Infection
Volume116
Issue number1
Publication statusPublished - Feb 1996
Externally publishedYes

Abstract

Genetic relationships amongst 115 mainly Australian isolates of Mycobacterium avium were assessed using multilocus enzyme electrophoresis (MEE). The isolates were divided into 58 electrophoretic types (ETs), with a mean genetic diversity of 0.29. Isolates from humans were closely related to but distinct from those cultured from birds, whilst some porcine isolates belonged to the same ETs as certain human isolates. Pulsed held gel electrophoresis (PFGE) was used to differentiate related isolates, and those from birds and some from other animals, including pigs, were distinguished from the human isolates. The results of MEE and PFGE suggested that certain strains of M. avium may be transmitted between birds and pigs, but there was no clear evidence of transmission to humans. The serovar of the M. avium isolates was not obviously related to their ET assignment or their PFGE type.

Citation Format(s)

Genetic characterization of Mycobacterium avium isolates recovered from humans and animals in Australia. / Feizabadi, M. M.; Robertson, I. D.; Cousins, D. V. et al.
In: Epidemiology and Infection, Vol. 116, No. 1, 02.1996, p. 41-49.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review