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Generation of cellular micropatterns on a single-layered graphene film

  • Daewha Hong
  • , Kieun Bae
  • , Sangjin Yoo
  • , Kyungtae Kang
  • , Byoungwook Jang
  • , Jinkyu Kim
  • , Sehun Kim
  • , Seokwoo Jeon
  • , Yoonkey Nam
  • , Yang-Gyun Kim
  • , Insung S. Choi*
  • *Corresponding author for this work

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

Abstract

Micropatterns of fibroblast and hippocampal neurons are generated on a single-layered graphene substrate. A large-area (1 cm × 1 cm) graphene film on Si/SiO2 is functionalized by surface-initiated ATRP of non-biofouling oligo(ethylene glycol) methacrylate, after grafting of the polymerization initiator bearing α-bromoisobutylate via photoreaction of the perfluorophenyl azide group. The microcontact printing-assisted spatio-selective reaction, after chemical activation of the terminal hydroxyl group of oligo(ethylene glycol) in the polymeric film, is utilized to generate the patterns of fibroblast and hippocampal neurons. 
Original languageEnglish
Pages (from-to)314-319
JournalMacromolecular Bioscience
Volume14
Issue number3
Online published30 Oct 2013
DOIs
Publication statusPublished - Mar 2014
Externally publishedYes

Research Keywords

  • aryl azide
  • cells
  • graphene
  • micropatterns
  • surface-initiated polymerization

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