Functional MRI Investigation of Audiovisual Interactions in Auditory Midbrain

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Celia M. Dong
  • Alex T. L. Leong
  • Leon C. Ho
  • Russell W. Chan
  • Yanqiu Feng
  • Patrick P. Gao
  • Ed X. Wu

Related Research Unit(s)

Detail(s)

Original languageEnglish
Pages (from-to)5527-5530
Journal / PublicationAnnual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Proceedings
Publication statusPublished - Jul 2018

Conference

Title2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
PlaceUnited States
CityHonolulu
Period18 - 21 July 2018

Abstract

The brain integrates information from different sensory modalities to form a representation of the environment and facilitate behavioral responses. The auditory midbrain or inferior colliculus (IC) is a pivotal station in the auditory system, integrating ascending and descending information from various auditory sources and cortical systems. The present study investigated the modulation of auditory responses in the IC by visual stimuli of different frequencies and intensities in rats using functional MRI (fMRI). Low-frequency (1 Hz) high-intensity visual stimulus suppressed IC auditory responses. However, high-frequency (10 Hz) or low-intensity visual stimuli did not alter the IC auditory responses. This finding demonstrates that cross-modal processing occurs in the IC in a manner that depends on the stimulus. Furthermore, only low-frequency high-intensity visual stimulus elicited responses in non-visual cortical regions, suggesting that the above cross-modal modulation effect may arise from top-down cortical feedback. These fMRI results provide insight to guide future studies of cross-modal processing in sensory pathways.

Bibliographic Note

Full text of this publication does not contain sufficient affiliation information. With consent from the author(s) concerned, the Research Unit(s) information for this record is based on the existing academic department affiliation of the author(s).

Citation Format(s)

Functional MRI Investigation of Audiovisual Interactions in Auditory Midbrain. / Dong, Celia M.; Leong, Alex T. L.; Manno, Francis Am; Lau, Condon; Ho, Leon C.; Chan, Russell W.; Feng, Yanqiu; Gao, Patrick P.; Wu, Ed X.

In: Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Proceedings, 07.2018, p. 5527-5530.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review