Fluorescent probes for detecting monoamine oxidase activity and cell imaging
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Author(s)
Detail(s)
Original language | English |
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Pages (from-to) | 2033-2036 |
Journal / Publication | Organic and Biomolecular Chemistry |
Volume | 12 |
Issue number | 13 |
Online published | 28 Jan 2014 |
Publication status | Published - 7 Apr 2014 |
Link(s)
Abstract
A series of new fluorogenic probes for monoamine oxidases (MAOs) were reported based on an oxidation and β-elimination mechanism. The limits of detection of the probes for MAO-A and -B were determined to be 3.5 and 6.0 μg mL-1 respectively. These probes displayed strong activity towards MAOs, especially MAO-B. Cellular imaging studies were also successfully conducted with MCF-7 cells. © 2014 The Royal Society of Chemistry.
Citation Format(s)
Fluorescent probes for detecting monoamine oxidase activity and cell imaging. / Li, Xuefeng; Zhang, Huatang; Xie, Yusheng et al.
In: Organic and Biomolecular Chemistry, Vol. 12, No. 13, 07.04.2014, p. 2033-2036.
In: Organic and Biomolecular Chemistry, Vol. 12, No. 13, 07.04.2014, p. 2033-2036.
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review