Fluorescent probes for detecting monoamine oxidase activity and cell imaging

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • Xuefeng Li
  • Huatang Zhang
  • Yi Hu
  • Qing Zhu

Detail(s)

Original languageEnglish
Pages (from-to)2033-2036
Journal / PublicationOrganic and Biomolecular Chemistry
Volume12
Issue number13
Online published28 Jan 2014
Publication statusPublished - 7 Apr 2014

Abstract

A series of new fluorogenic probes for monoamine oxidases (MAOs) were reported based on an oxidation and β-elimination mechanism. The limits of detection of the probes for MAO-A and -B were determined to be 3.5 and 6.0 μg mL-1 respectively. These probes displayed strong activity towards MAOs, especially MAO-B. Cellular imaging studies were also successfully conducted with MCF-7 cells. © 2014 The Royal Society of Chemistry.

Citation Format(s)

Fluorescent probes for detecting monoamine oxidase activity and cell imaging. / Li, Xuefeng; Zhang, Huatang; Xie, Yusheng et al.
In: Organic and Biomolecular Chemistry, Vol. 12, No. 13, 07.04.2014, p. 2033-2036.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review