Finding transcription factor binding sites with indels

Wangsen Feng; Lusheng Wang; Wanling Qu; Hanpin Wang

doi:10.1109/ICBBE.2007.69

Finding transcription factor binding sites with indels

Wangsen Feng
, Lusheng Wang
, Wanling Qu
, Hanpin Wang

Department of Computer Science

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

Abstract

Finding transcription factor binding sites is of great importance for biologists to understand gene expression regulatory mechanisms. Usually, researchers design algorithms to detect transcription factor biding sites with substitution mutations only, based on the conserved property of biological functional sequences. In this paper, we propose a randomized algorithm to find biding sites with indels. A tool is also developed to evaluate the performance of the algorithm based on simulated datasets. © 2007 IEEE.

Original language	English
Title of host publication	2007 1st International Conference on Bioinformatics and Biomedical Engineering, ICBBE
Pages	256-259
DOIs	https://doi.org/10.1109/ICBBE.2007.69
Publication status	Published - 2007
Event	2007 1st International Conference on Bioinformatics and Biomedical Engineering, ICBBE - Wuhan, China Duration: 6 Jul 2007 → 8 Jul 2007

Conference

Conference	2007 1st International Conference on Bioinformatics and Biomedical Engineering, ICBBE
Place	China
City	Wuhan
Period	6/07/07 → 8/07/07

Research Keywords

Indel
Motif
Transcription factor binding sites

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10.1109/ICBBE.2007.69

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@inproceedings{6b1076e89f7a4c0194d4f945c5c59848,

title = "Finding transcription factor binding sites with indels",

abstract = "Finding transcription factor binding sites is of great importance for biologists to understand gene expression regulatory mechanisms. Usually, researchers design algorithms to detect transcription factor biding sites with substitution mutations only, based on the conserved property of biological functional sequences. In this paper, we propose a randomized algorithm to find biding sites with indels. A tool is also developed to evaluate the performance of the algorithm based on simulated datasets. {\textcopyright} 2007 IEEE.",

keywords = "Indel, Motif, Transcription factor binding sites",

author = "Wangsen Feng and Lusheng Wang and Wanling Qu and Hanpin Wang",

year = "2007",

doi = "10.1109/ICBBE.2007.69",

language = "English",

isbn = "1424411203",

pages = "256--259",

booktitle = "2007 1st International Conference on Bioinformatics and Biomedical Engineering, ICBBE",

note = "2007 1st International Conference on Bioinformatics and Biomedical Engineering, ICBBE ; Conference date: 06-07-2007 Through 08-07-2007",

}

Finding transcription factor binding sites with indels. / Feng, Wangsen; Wang, Lusheng; Qu, Wanling et al.
2007 1st International Conference on Bioinformatics and Biomedical Engineering, ICBBE. 2007. p. 256-259 4272553.

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

TY - GEN

T1 - Finding transcription factor binding sites with indels

AU - Feng, Wangsen

AU - Wang, Lusheng

AU - Qu, Wanling

AU - Wang, Hanpin

PY - 2007

Y1 - 2007

N2 - Finding transcription factor binding sites is of great importance for biologists to understand gene expression regulatory mechanisms. Usually, researchers design algorithms to detect transcription factor biding sites with substitution mutations only, based on the conserved property of biological functional sequences. In this paper, we propose a randomized algorithm to find biding sites with indels. A tool is also developed to evaluate the performance of the algorithm based on simulated datasets. © 2007 IEEE.

AB - Finding transcription factor binding sites is of great importance for biologists to understand gene expression regulatory mechanisms. Usually, researchers design algorithms to detect transcription factor biding sites with substitution mutations only, based on the conserved property of biological functional sequences. In this paper, we propose a randomized algorithm to find biding sites with indels. A tool is also developed to evaluate the performance of the algorithm based on simulated datasets. © 2007 IEEE.

KW - Indel

KW - Motif

KW - Transcription factor binding sites

UR - https://www.scopus.com/pages/publications/35348892091

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-35348892091&origin=recordpage

U2 - 10.1109/ICBBE.2007.69

DO - 10.1109/ICBBE.2007.69

M3 - RGC 32 - Refereed conference paper (with host publication)

SN - 1424411203

SN - 9781424411207

SP - 256

EP - 259

BT - 2007 1st International Conference on Bioinformatics and Biomedical Engineering, ICBBE

T2 - 2007 1st International Conference on Bioinformatics and Biomedical Engineering, ICBBE

Y2 - 6 July 2007 through 8 July 2007

ER -

Finding transcription factor binding sites with indels

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