Feline Immunodeficiency Virus : Current Knowledge and Future Directions
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Author(s)
Related Research Unit(s)
Detail(s)
| Original language | English |
|---|---|
| Pages (from-to) | 145-159 |
| Number of pages | 15 |
| Journal / Publication | Advances in Small Animal Care |
| Volume | 3 |
| Issue number | 1 |
| Online published | 31 Oct 2022 |
| Publication status | Published - Nov 2022 |
Link(s)
| DOI | DOI |
|---|---|
| Attachment(s) | Documents
Publisher's Copyright Statement
|
| Permanent Link | https://scholars.cityu.edu.hk/en/publications/publication(8e1ef92a-7aff-44f6-9610-5bbfdf8be33d).html |
Abstract
• Clinical outcomes in FIV-infected cats are variable and poorly defined. The immunodeficiency that accompanies infection can, and often does, remain subclinical.
• FIV infection is lifelong. Serology is the first-line diagnostic test to identify infected cats. PCR is available for confirmation if required.
• Viral, host, and environmental factors that influence prognosis in individual FIV-infected cats are unclear. Reliable surrogate markers to predict clinical progression are not available.
• Key to the management of FIV-infected cats is preventive health care and early detection and investigation of clinical problems.
• A commercial FIV vaccine is available in only a few regions including Australia, New Zealand, and Japan. Interference with diagnostic testing by the commercial FIV vaccine is largely resolved, but vaccine efficacy in the field remains questionable. FIV vaccination is classified as noncore by WSAVA Vaccination Guidelines Group.
• FIV infection is lifelong. Serology is the first-line diagnostic test to identify infected cats. PCR is available for confirmation if required.
• Viral, host, and environmental factors that influence prognosis in individual FIV-infected cats are unclear. Reliable surrogate markers to predict clinical progression are not available.
• Key to the management of FIV-infected cats is preventive health care and early detection and investigation of clinical problems.
• A commercial FIV vaccine is available in only a few regions including Australia, New Zealand, and Japan. Interference with diagnostic testing by the commercial FIV vaccine is largely resolved, but vaccine efficacy in the field remains questionable. FIV vaccination is classified as noncore by WSAVA Vaccination Guidelines Group.
Research Area(s)
- Retrovirus, Lentivirus, Immunodeficiency, Viral diversity, Receptor usage, CD134, CXCR4, Vaccine
Citation Format(s)
Feline Immunodeficiency Virus : Current Knowledge and Future Directions. / Bęczkowski, Paweł M.; Beatty, Julia A.
In: Advances in Small Animal Care, Vol. 3, No. 1, 11.2022, p. 145-159.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
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