Feeding a diet with decreased protein content reduces indices of protein fermentation and the incidence of postweaning diarrhea in weaned pigs challenged with an enterotoxigenic strain of Escherichia coli

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • J. M. Heo
  • J. C. Kim
  • C. F. Hansen
  • B. P. Mullan
  • J. R. Pluske

Detail(s)

Original languageEnglish
Pages (from-to)2833-2843
Journal / PublicationJournal of Animal Science
Volume87
Issue number9
Publication statusPublished - Sep 2009
Externally publishedYes

Abstract

This study evaluated the effect of feeding low protein (LP) diets for 7 or 14 d after weaning or a high protein (HP) diet for 14 d after weaning on postweaning diarrhea (PWD), indices of protein fermentation, and production in pigs infected or not infected per os with an enterotoxigenic strain of Escherichia coli. A total of 72 female pigs weaned at aged 21 d with initial BW of 5.9 ± 0.12 kg were used in a 3 × 2 factorial arrangement of treatments. The factors were 3 feeding regimens associated with different combinations of feeding duration and diet CP level: (i) HP diet (256 g of CP/kg) fed for 14 d after weaning, (ii) LP diet (175 g of CP/kg) fed for 7 d after weaning, and (iii) LP diet fed for 14 d after weaning; and infection or noninfection with an enterotoxigenic strain of E. coli (107 cfu/mL, serotype O149:K91:K88) at 72, 96, and 120 h after weaning. The LP diets were fortified with crystalline Ile and Val to achieve an ideal AA pattern. A second-stage diet (213 g of CP/kg) was fed to pigs at the conclusion of each feeding regimen, and the study finished 4 wk after weaning. None of the diets contained antimicrobials. Feeding the LP diets decreased (P < 0.001) plasma urea nitrogen, fecal ammonia nitrogen concentrations, and the incidence of PWD, but increased (P = 0.001) fecal DM content compared with pigs fed HP in the 2-wk period after weaning. Infection increased shedding of β-hemolytic E. coli (P < 0.001), the incidence of PWD (P < 0.001), and fecal ammonia nitrogen concentrations (P < 0.01), but did not interact with feeding regimen, after weaning. Pigs challenged with E. coli grew more slowly (P < 0.001) and had decreased G:F (P < 0.01) compared with nonchallenged pigs in the 4-wk period after weaning. Feeding an LP diet for 7 or 14 d after weaning markedly reduced the incidence of PWD after infection with β-hemolytic E. coli. Infection was associated with decreased indices of protein fermentation in the distal gastrointestinal tract but did not compromise the growth of weaner pigs in the 4-wk period after weaning.

Research Area(s)

  • Escherichia coli, Infection, Low protein, Pig, Postweaning diarrhea, Production

Citation Format(s)

Feeding a diet with decreased protein content reduces indices of protein fermentation and the incidence of postweaning diarrhea in weaned pigs challenged with an enterotoxigenic strain of Escherichia coli. / Heo, J. M.; Kim, J. C.; Hansen, C. F.; Mullan, B. P.; Hampson, D. J.; Pluske, J. R.

In: Journal of Animal Science, Vol. 87, No. 9, 09.2009, p. 2833-2843.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review