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Fast voice-coil scanning optical-resolution photoacoustic microscopy

  • Lidai Wang
  • , Konstantin Maslov
  • , Junjie Yao
  • , Bin Rao
  • , Lihong V. Wang

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

Abstract

We developed a photoacoustic imaging system that has real-time imaging capability with optical resolution. The imaging system is capable of scanning at 20 Hz over a 9mm range and up to 40 Hz over a 1mm scanning range. A focused laser beam provides a lateral resolution of 3:4 μm as measured in an optically nonscattering medium. Flows of micrometer-sized carbon particles or whole blood in a silicone tube and individual red blood cells (RBCs) in mouse ear capillaries were also imaged in real time, demonstrating the capability to image highly dynamic processes in vivo at a micrometer-scale resolution. © 2011 Optical Society of America.
Original languageEnglish
Pages (from-to)139-141
JournalOptics Letters
Volume36
Issue number2
DOIs
Publication statusPublished - 15 Jan 2011
Externally publishedYes

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