Fabrication of pseudo three-dimensional PADC cell culture substrates for dosimetric studies

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

3 Scopus Citations
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Author(s)

  • C. K M Ng
  • M. Y P Wong
  • R. K K Lam
  • J. P Y Ho
  • K. N. Yu

Detail(s)

Original languageEnglish
Pages (from-to)1790-1794
Journal / PublicationRadiation Measurements
Volume46
Issue number12
Publication statusPublished - Dec 2011

Abstract

Pseudo three-dimensional (3D) polyallyldiglycol carbonate (PADC) cell culture substrates were fabricated by creating micrometer-size pores on thin PADC films by alpha-particle irradiation and subsequent chemical etching. Our results showed comparatively fewer 53BP1 foci in alpha-particle irradiated as well as bystander HeLa cells cultured on pseudo 3D PADC substrates than in those cultured on two-dimensional substrates. © 2011 Elsevier Ltd. All rights reserved.

Research Area(s)

  • 53BP1, Alpha particles, CR-39, HeLa cells, PADC

Citation Format(s)

Fabrication of pseudo three-dimensional PADC cell culture substrates for dosimetric studies. / Ng, C. K M; Wong, M. Y P; Lam, R. K K et al.
In: Radiation Measurements, Vol. 46, No. 12, 12.2011, p. 1790-1794.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review