Fabrication of pseudo three-dimensional PADC cell culture substrates for dosimetric studies
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Author(s)
Detail(s)
Original language | English |
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Pages (from-to) | 1790-1794 |
Journal / Publication | Radiation Measurements |
Volume | 46 |
Issue number | 12 |
Publication status | Published - Dec 2011 |
Link(s)
Abstract
Pseudo three-dimensional (3D) polyallyldiglycol carbonate (PADC) cell culture substrates were fabricated by creating micrometer-size pores on thin PADC films by alpha-particle irradiation and subsequent chemical etching. Our results showed comparatively fewer 53BP1 foci in alpha-particle irradiated as well as bystander HeLa cells cultured on pseudo 3D PADC substrates than in those cultured on two-dimensional substrates. © 2011 Elsevier Ltd. All rights reserved.
Research Area(s)
- 53BP1, Alpha particles, CR-39, HeLa cells, PADC
Citation Format(s)
Fabrication of pseudo three-dimensional PADC cell culture substrates for dosimetric studies. / Ng, C. K M; Wong, M. Y P; Lam, R. K K et al.
In: Radiation Measurements, Vol. 46, No. 12, 12.2011, p. 1790-1794.
In: Radiation Measurements, Vol. 46, No. 12, 12.2011, p. 1790-1794.
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review