Fabrication of micropillar substrates using replicas of alpha-particle irradiated and chemically etched PADC films

C. K M Ng; E. Y W Chong; V. A L Roy; K. M C Cheung; K. W K Yeung; K. N. Yu

doi:10.1016/j.apradiso.2011.11.019

Author(s)

C. K M Ng
E. Y W Chong
K. M C Cheung
K. W K Yeung

Detail(s)

Original language	English
Pages (from-to)	1432-1435
Journal / Publication	Applied Radiation and Isotopes
Volume	70
Issue number	7
Publication status	Published - Jul 2012

Link(s)

DOI	DOI https://doi.org/10.1016/j.apradiso.2011.11.019 Final Published version
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Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-84862155947&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(2354ad26-13b7-4a95-892d-b19600bb8f0f).html

Abstract

We proposed a simple method to fabricate micropillar substrates. Polyallyldiglycol carbonate (PADC) films were irradiated by alpha particles and then chemically etched to form a cast with micron-scale spherical pores. A polydimethylsiloxane (PDMS) replica of this PADC film gave a micropillar substrate with micron-scale spherical pillars. HeLa cells cultured on such a micropillar substrate had significantly larger percentage of cells entering S-phase, attached cell numbers and cell spreading areas. © 2011 Elsevier Ltd.

Research Area(s)

Alpha particle, Cell proliferation, HeLa cells, Micropillar substrate, PADC, PDMS

Citation Format(s)

[ RIS ] [ BibTeX ]

Fabrication of micropillar substrates using replicas of alpha-particle irradiated and chemically etched PADC films. / Ng, C. K M; Chong, E. Y W; Roy, V. A L et al.
In: Applied Radiation and Isotopes, Vol. 70, No. 7, 07.2012, p. 1432-1435.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Ng, CKM, Chong, EYW, Roy, VAL, Cheung, KMC, Yeung, KWK & Yu, KN 2012, 'Fabrication of micropillar substrates using replicas of alpha-particle irradiated and chemically etched PADC films', Applied Radiation and Isotopes, vol. 70, no. 7, pp. 1432-1435. https://doi.org/10.1016/j.apradiso.2011.11.019

Ng, C. K. M., Chong, E. Y. W., Roy, V. A. L., Cheung, K. M. C., Yeung, K. W. K., & Yu, K. N. (2012). Fabrication of micropillar substrates using replicas of alpha-particle irradiated and chemically etched PADC films. Applied Radiation and Isotopes, 70(7), 1432-1435. https://doi.org/10.1016/j.apradiso.2011.11.019

Ng CKM, Chong EYW, Roy VAL, Cheung KMC, Yeung KWK, Yu KN. Fabrication of micropillar substrates using replicas of alpha-particle irradiated and chemically etched PADC films. Applied Radiation and Isotopes. 2012 Jul;70(7):1432-1435. doi: 10.1016/j.apradiso.2011.11.019

Ng, C. K M ; Chong, E. Y W ; Roy, V. A L et al. / Fabrication of micropillar substrates using replicas of alpha-particle irradiated and chemically etched PADC films. In: Applied Radiation and Isotopes. 2012 ; Vol. 70, No. 7. pp. 1432-1435.