Fabrication of a silver octahedral nanoparticle-containing polycaprolactone nanocomposite for antibacterial bone scaffolds

Yu Gao; Ammar Mansoor Hassanbhai; Jing Lim; Lianhui Wang; Chenjie Xu

doi:10.1039/C6RA26063B

Fabrication of a silver octahedral nanoparticle-containing polycaprolactone nanocomposite for antibacterial bone scaffolds

Yu Gao
, Ammar Mansoor Hassanbhai
, Jing Lim
, Lianhui Wang^*
, Chenjie Xu^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

16 Citations (Scopus)

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Abstract

This work investigated the antimicrobial activity of Ag octahedral nanoparticle containing polycaprolactone scaffolds (Ag-PCL) that is fabricated via cryomilling. The fabricated composite scaffolds exhibited localized antibacterial activity with no adverse effects on viability and osteogenic differentiation of human fetal mesenchymal stem cells (hfMSCs). Compared to plain PCL scaffolds, the Ag-PCL scaffolds significantly reduce bacteria survival to 32.2% over a 4 hour incubation.

Original language	English
Pages (from-to)	10051-10056
Journal	RSC Advances
Volume	7
Issue number	17
Online published	6 Feb 2017
DOIs	https://doi.org/10.1039/C6RA26063B
Publication status	Published - 2017
Externally published	Yes

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This full text is made available under CC-BY-NC 3.0. https://creativecommons.org/licenses/by-nc/3.0/

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title = "Fabrication of a silver octahedral nanoparticle-containing polycaprolactone nanocomposite for antibacterial bone scaffolds",

abstract = "This work investigated the antimicrobial activity of Ag octahedral nanoparticle containing polycaprolactone scaffolds (Ag-PCL) that is fabricated via cryomilling. The fabricated composite scaffolds exhibited localized antibacterial activity with no adverse effects on viability and osteogenic differentiation of human fetal mesenchymal stem cells (hfMSCs). Compared to plain PCL scaffolds, the Ag-PCL scaffolds significantly reduce bacteria survival to 32.2\% over a 4 hour incubation.",

author = "Yu Gao and Hassanbhai, \{Ammar Mansoor\} and Jing Lim and Lianhui Wang and Chenjie Xu",

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T1 - Fabrication of a silver octahedral nanoparticle-containing polycaprolactone nanocomposite for antibacterial bone scaffolds

AU - Gao, Yu

AU - Hassanbhai, Ammar Mansoor

AU - Lim, Jing

AU - Wang, Lianhui

AU - Xu, Chenjie

PY - 2017

Y1 - 2017

N2 - This work investigated the antimicrobial activity of Ag octahedral nanoparticle containing polycaprolactone scaffolds (Ag-PCL) that is fabricated via cryomilling. The fabricated composite scaffolds exhibited localized antibacterial activity with no adverse effects on viability and osteogenic differentiation of human fetal mesenchymal stem cells (hfMSCs). Compared to plain PCL scaffolds, the Ag-PCL scaffolds significantly reduce bacteria survival to 32.2% over a 4 hour incubation.

AB - This work investigated the antimicrobial activity of Ag octahedral nanoparticle containing polycaprolactone scaffolds (Ag-PCL) that is fabricated via cryomilling. The fabricated composite scaffolds exhibited localized antibacterial activity with no adverse effects on viability and osteogenic differentiation of human fetal mesenchymal stem cells (hfMSCs). Compared to plain PCL scaffolds, the Ag-PCL scaffolds significantly reduce bacteria survival to 32.2% over a 4 hour incubation.

UR - https://www.scopus.com/pages/publications/85012031561

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85012031561&origin=recordpage

U2 - 10.1039/C6RA26063B

DO - 10.1039/C6RA26063B

M3 - RGC 21 - Publication in refereed journal

SN - 2046-2069

VL - 7

SP - 10051

EP - 10056

JO - RSC Advances

JF - RSC Advances

IS - 17

ER -

Fabrication of a silver octahedral nanoparticle-containing polycaprolactone nanocomposite for antibacterial bone scaffolds

Abstract

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