Eye-chamber-on-a-chip by microfluidic co-culture of retinal cells

HC Shum

doi:10.3390/optofluidics2017-04523

Eye-chamber-on-a-chip by microfluidic co-culture of retinal cells

HC Shum

Research output: Conference Papers › RGC 32 - Refereed conference paper (without host publication) › peer-review

Abstract

The human eye is an important and yet difficult organ to study in situ. Microfluidic technologies provide the tool to model the human eye and allow the simultaneous observation of cellular behaviors under different physiological conditions. In this talk, I will share some of the conditions that are needed for constructing a physiologically relevant in vitro eye model. The model will be used to study the effects of saccadic eye movement and hydrostatics on the fluidic and cellular behaviors on-chip. The ability to control, observe, measure and monitor the relevant variables on a microfluidic chip enables the potential to understand the physo-chemical and fluid mechanical origins of conditions often observed in the human eye, and suggest new therapeutic and surgical strategies.

Original language	English
DOIs	https://doi.org/10.3390/optofluidics2017-04523
Publication status	Published - 25 Jul 2017
Externally published	Yes
Event	The 7th International Multidisciplinary Conference on Optofluidics 2017 - Singapore, Singapore Duration: 25 Jul 2017 → 28 Jul 2017

Conference

Conference	The 7th International Multidisciplinary Conference on Optofluidics 2017
Place	Singapore
City	Singapore
Period	25/07/17 → 28/07/17

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

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title = "Eye-chamber-on-a-chip by microfluidic co-culture of retinal cells",

abstract = "The human eye is an important and yet difficult organ to study in situ. Microfluidic technologies provide the tool to model the human eye and allow the simultaneous observation of cellular behaviors under different physiological conditions. In this talk, I will share some of the conditions that are needed for constructing a physiologically relevant in vitro eye model. The model will be used to study the effects of saccadic eye movement and hydrostatics on the fluidic and cellular behaviors on-chip. The ability to control, observe, measure and monitor the relevant variables on a microfluidic chip enables the potential to understand the physo-chemical and fluid mechanical origins of conditions often observed in the human eye, and suggest new therapeutic and surgical strategies.",

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N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

PY - 2017/7/25

Y1 - 2017/7/25

N2 - The human eye is an important and yet difficult organ to study in situ. Microfluidic technologies provide the tool to model the human eye and allow the simultaneous observation of cellular behaviors under different physiological conditions. In this talk, I will share some of the conditions that are needed for constructing a physiologically relevant in vitro eye model. The model will be used to study the effects of saccadic eye movement and hydrostatics on the fluidic and cellular behaviors on-chip. The ability to control, observe, measure and monitor the relevant variables on a microfluidic chip enables the potential to understand the physo-chemical and fluid mechanical origins of conditions often observed in the human eye, and suggest new therapeutic and surgical strategies.

AB - The human eye is an important and yet difficult organ to study in situ. Microfluidic technologies provide the tool to model the human eye and allow the simultaneous observation of cellular behaviors under different physiological conditions. In this talk, I will share some of the conditions that are needed for constructing a physiologically relevant in vitro eye model. The model will be used to study the effects of saccadic eye movement and hydrostatics on the fluidic and cellular behaviors on-chip. The ability to control, observe, measure and monitor the relevant variables on a microfluidic chip enables the potential to understand the physo-chemical and fluid mechanical origins of conditions often observed in the human eye, and suggest new therapeutic and surgical strategies.

U2 - 10.3390/optofluidics2017-04523

DO - 10.3390/optofluidics2017-04523

M3 - RGC 32 - Refereed conference paper (without host publication)

T2 - The 7th International Multidisciplinary Conference on Optofluidics 2017

Y2 - 25 July 2017 through 28 July 2017

ER -

Eye-chamber-on-a-chip by microfluidic co-culture of retinal cells

Abstract

Conference

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