Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells

David G. Smith; Ga-Lai Law; Benjamin S. Murray; Robert Pal; David Parker; Ka-Leung Wong

doi:10.1039/c1cc11853f

Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells

David G. Smith
, Ga-Lai Law
, Benjamin S. Murray
, Robert Pal
, David Parker
, Ka-Leung Wong

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

46 Citations (Scopus)

Abstract

Image and spectral intensity from bicarbonate-selective europium(iii) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO₂, and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide. © 2011 The Royal Society of Chemistry.

Original language	English
Pages (from-to)	7347-7349
Journal	Chemical Communications
Volume	47
Issue number	26
DOIs	https://doi.org/10.1039/c1cc11853f
Publication status	Published - 14 Jul 2011
Externally published	Yes

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Funding

We thank the Royal Society (KLW), the ERC (FCC: 266804) and EPSRC for support (DGS).

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abstract = "Image and spectral intensity from bicarbonate-selective europium(iii) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO2, and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide. {\textcopyright} 2011 The Royal Society of Chemistry.",

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AU - Murray, Benjamin S.

AU - Pal, Robert

AU - Parker, David

AU - Wong, Ka-Leung

N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

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N2 - Image and spectral intensity from bicarbonate-selective europium(iii) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO2, and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide. © 2011 The Royal Society of Chemistry.

AB - Image and spectral intensity from bicarbonate-selective europium(iii) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO2, and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide. © 2011 The Royal Society of Chemistry.

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JO - Chemical Communications

JF - Chemical Communications

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ER -

Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells

Abstract

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