Establishment of diagnostic criteria for feline nonflea-induced hypersensitivity dermatitis

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Claude Favrot
  • Jean Steffan
  • Wolfgang Seewald
  • Monika Linek
  • Geneviève Marignac
  • Thierry Olivry
  • Luc Beco
  • Claudia Nett
  • Jacques Fontaine
  • Petra Roosje
  • Kerstin Bergvall
  • Svetlana Belova
  • Stefanie Koebrich
  • Didier Pin
  • Marcel Kovalik
  • Sabrina Meury
  • Sylvia Wilhelm

Detail(s)

Original languageEnglish
Pages (from-to)45-50, e11
Journal / PublicationVeterinary Dermatology
Volume23
Issue number1
Online published7 Sep 2011
Publication statusPublished - Feb 2012
Externally publishedYes

Abstract

Hypersensitivity dermatitides (HD) are commonly seen in cats, and they are usually caused by environmental, food and/or flea allergens. Affected cats normally present with one of the following clinical reaction patterns: head and neck excoriations, usually symmetrical self-induced alopecia, eosinophilic skin lesions or miliary dermatitis. Importantly, none of these clinical presentations is considered to be pathognomonic for HD skin diseases, and the diagnosis of HD is usually based on the exclusion of other pruritic diseases and on a positive response to therapy. The objectives of this study were to propose sets of criteria for the diagnosis of nonflea-induced HD (NFHD). We recruited 501 cats with pruritus and skin lesions and compared clinical parameters between cats with NFHD (encompassing those with nonflea, nonfood HD and those with food HD), flea HD and other pruritic conditions. Using simulated annealing techniques, we established two sets of proposed criteria for the following two different clinical situations: (i)the diagnosis of NFHD in a population of pruritic cats; and (ii)the diagnosis of NFHD after exclusion of cats with flea HD. These criteria sets were associated with good sensitivity and specificity and may be useful for homogeneity of enrolment in clinical trials and to evaluate the probability of diagnosis of NFHD in clinical practice. Finally, these criteria were not useful to differentiate cats with NFHD from those with food HD. © 2011 The Authors. Veterinary Dermatology © 2011 ESVD and ACVD.

Citation Format(s)

Establishment of diagnostic criteria for feline nonflea-induced hypersensitivity dermatitis. / Favrot, Claude; Steffan, Jean; Seewald, Wolfgang; Hobi, Stefan; Linek, Monika; Marignac, Geneviève; Olivry, Thierry; Beco, Luc; Nett, Claudia; Fontaine, Jacques; Roosje, Petra; Bergvall, Kerstin; Belova, Svetlana; Koebrich, Stefanie; Pin, Didier; Kovalik, Marcel; Meury, Sabrina; Wilhelm, Sylvia.

In: Veterinary Dermatology, Vol. 23, No. 1, 02.2012, p. 45-50, e11.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review