Equine arteritis virus

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)93-122
Journal / PublicationVeterinary Microbiology
Volume167
Issue number1-2
Online published3 Jul 2013
Publication statusPublished - 29 Nov 2013
Externally publishedYes

Abstract

Equine arteritis virus (EAV) is the causative agent of equine viral arteritis (EVA), a respiratory and reproductive disease of equids. There has been significant recent progress in understanding the molecular biology of EAV and the pathogenesis of its infection in horses. In particular, the use of contemporary genomic techniques, along with the development and reverse genetic manipulation of infectious cDNA clones of several strains of EAV, has generated significant novel information regarding the basic molecular biology of the virus. Therefore, the objective of this review is to summarize current understanding of EAV virion architecture, replication, evolution, molecular epidemiology and genetic variation, pathogenesis including the influence of host genetics on disease susceptibility, host immune response, and potential vaccination and treatment strategies.

Research Area(s)

  • EAV, Equine arteritis virus, EVA

Citation Format(s)

Equine arteritis virus. / Balasuriya, Udeni B.R.; Go, Yun Young; MacLachlan, N. James.

In: Veterinary Microbiology, Vol. 167, No. 1-2, 29.11.2013, p. 93-122.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review