TY - JOUR
T1 - Enhanced core-shell nano-conductive piezoelectric sensor via self-oriented beta phase nanocrystals for real-time monitoring of physiological signals
AU - Khan, Bangul
AU - Hilal, Mohamed Elhousseini
AU - Ahmed, Syed Bilal
AU - Ahmad, Rafi U Shan
AU - Lyu, Liangyi
AU - Chen, Hanjie
AU - Khan, Bilawal
AU - Gunasekaran, Iyappan
AU - Feng, Chuhan
AU - LIU, Shiyuan
AU - Yang, Zhengbao
AU - Khoo, Bee Luan
PY - 2025/6
Y1 - 2025/6
N2 - Piezoelectric materials have garnered significant attention due to their exceptional mechanical, electrical, and flexible properties, making them ideal for real-time monitoring of human physiological signals. However, accurately detecting the pattern of physiological signals remains a significant challenge. In this study, we introduce a novel Nano piezo-channelling approach by harnessing the concept of deeply disturbing piezo electrons and exploiting a nano-conductive channel within complex core–shell nanofibers. By systematically enhancing the β-phase of poly (vinylidene fluoride) (PVDF) through concentration variation and doping with ammonium salt HHE and integrating polyacrylonitrile (PAN) and copper (Cu) nanoparticles as conductive channels, we have successfully achieved higher beta phase (96.3 %) with the accurate pattern detection of physiological signals The resulting piezoelectric pressure sensor demonstrated a remarkable sensitivity of 3.76 V/N, with response and recovery times of less than 45 ms, and maintained stability over 18,000 cycles. This advanced sensor detected various physiological signals with accurate patterns, including radial, carotid, brachial, temporal, tibial, and popliteal pulse waves and joint movements. To evaluate the quality of these pulse wave signals, we developed a deep recurrent neural network (DRNN) model to predict blood pressure (BP) using pulse wave signals (n = 20), validating the sensor’s accuracy and precision. By enabling accurate, real-time detection of diverse physiological signals, Piezo-channeling-based sensors hold great potential for transforming personalized healthcare, particularly in non-invasive cardiovascular monitoring and the broader field of remote patient monitoring.© 2025 Published by Elsevier B.V.
AB - Piezoelectric materials have garnered significant attention due to their exceptional mechanical, electrical, and flexible properties, making them ideal for real-time monitoring of human physiological signals. However, accurately detecting the pattern of physiological signals remains a significant challenge. In this study, we introduce a novel Nano piezo-channelling approach by harnessing the concept of deeply disturbing piezo electrons and exploiting a nano-conductive channel within complex core–shell nanofibers. By systematically enhancing the β-phase of poly (vinylidene fluoride) (PVDF) through concentration variation and doping with ammonium salt HHE and integrating polyacrylonitrile (PAN) and copper (Cu) nanoparticles as conductive channels, we have successfully achieved higher beta phase (96.3 %) with the accurate pattern detection of physiological signals The resulting piezoelectric pressure sensor demonstrated a remarkable sensitivity of 3.76 V/N, with response and recovery times of less than 45 ms, and maintained stability over 18,000 cycles. This advanced sensor detected various physiological signals with accurate patterns, including radial, carotid, brachial, temporal, tibial, and popliteal pulse waves and joint movements. To evaluate the quality of these pulse wave signals, we developed a deep recurrent neural network (DRNN) model to predict blood pressure (BP) using pulse wave signals (n = 20), validating the sensor’s accuracy and precision. By enabling accurate, real-time detection of diverse physiological signals, Piezo-channeling-based sensors hold great potential for transforming personalized healthcare, particularly in non-invasive cardiovascular monitoring and the broader field of remote patient monitoring.© 2025 Published by Elsevier B.V.
KW - Piezoelectric
KW - Core-shell
KW - Physiological signal monitoring
KW - Nanocrystals
KW - Deep recurrent neural network (DRNN)
UR - http://www.scopus.com/inward/record.url?scp=105002854616&partnerID=8YFLogxK
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-105002854616&origin=recordpage
U2 - 10.1016/j.cej.2025.162384
DO - 10.1016/j.cej.2025.162384
M3 - RGC 21 - Publication in refereed journal
SN - 1385-8947
VL - 513
JO - Chemical Engineering Journal
JF - Chemical Engineering Journal
M1 - 162384
ER -