Emergence of conjugative IncC type plasmid simultaneously encoding resistance to ciprofloxacin, ceftriaxone and azithromycin in Salmonella

Kaichao Chen; Chen Yang; Edward Waichi Chan; Sheng Chen

doi:10.1128/AAC.01046-21

Emergence of conjugative IncC type plasmid simultaneously encoding resistance to ciprofloxacin, ceftriaxone and azithromycin in Salmonella

Kaichao Chen
, Chen Yang
, Edward Waichi Chan
, Sheng Chen^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

12 Citations (Scopus)

Abstract

Non-typical Salmonella is a primary cause of food-borne diseases and considered as a major public health concern worldwide (1, 2). The current choices of treatment for systemic Salmonella infections are ciprofloxacin, ceftriaxone, and azithromycin (3). Clinical Salmonella isolates resistant to these three antibiotics have been detected occasionally in recent years, but cotransfer of such three antimicrobial resistance determinants in one plasmid was rarely reported (4).

Original language	English
Article number	01046
Journal	Antimicrobial Agents and Chemotherapy
Volume	65
Issue number	9
Online published	14 Jun 2021
DOIs	https://doi.org/10.1128/AAC.01046-21
Publication status	Published - Aug 2021

Research Keywords

Azithromycin
Ceftriaxone
Ciprofloxacin
Conjugative plasmid
IncC type
Salmonella

RGC Funding Information

RGC-funded

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10.1128/AAC.01046-21

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@article{d73b103f70dc496e93bf95c13d0ebde1,

title = "Emergence of conjugative IncC type plasmid simultaneously encoding resistance to ciprofloxacin, ceftriaxone and azithromycin in Salmonella",

abstract = "Non-typical Salmonella is a primary cause of food-borne diseases and considered as a major public health concern worldwide (1, 2). The current choices of treatment for systemic Salmonella infections are ciprofloxacin, ceftriaxone, and azithromycin (3). Clinical Salmonella isolates resistant to these three antibiotics have been detected occasionally in recent years, but cotransfer of such three antimicrobial resistance determinants in one plasmid was rarely reported (4).",

keywords = "Azithromycin, Ceftriaxone, Ciprofloxacin, Conjugative plasmid, IncC type, Salmonella",

author = "Kaichao Chen and Chen Yang and Chan, \{Edward Waichi\} and Sheng Chen",

year = "2021",

month = aug,

doi = "10.1128/AAC.01046-21",

language = "English",

volume = "65",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "9",

}

Emergence of conjugative IncC type plasmid simultaneously encoding resistance to ciprofloxacin, ceftriaxone and azithromycin in Salmonella. / Chen, Kaichao; Yang, Chen; Chan, Edward Waichi et al.
In: Antimicrobial Agents and Chemotherapy, Vol. 65, No. 9, 01046, 08.2021.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

TY - JOUR

T1 - Emergence of conjugative IncC type plasmid simultaneously encoding resistance to ciprofloxacin, ceftriaxone and azithromycin in Salmonella

AU - Chen, Kaichao

AU - Yang, Chen

AU - Chan, Edward Waichi

AU - Chen, Sheng

PY - 2021/8

Y1 - 2021/8

N2 - Non-typical Salmonella is a primary cause of food-borne diseases and considered as a major public health concern worldwide (1, 2). The current choices of treatment for systemic Salmonella infections are ciprofloxacin, ceftriaxone, and azithromycin (3). Clinical Salmonella isolates resistant to these three antibiotics have been detected occasionally in recent years, but cotransfer of such three antimicrobial resistance determinants in one plasmid was rarely reported (4).

AB - Non-typical Salmonella is a primary cause of food-borne diseases and considered as a major public health concern worldwide (1, 2). The current choices of treatment for systemic Salmonella infections are ciprofloxacin, ceftriaxone, and azithromycin (3). Clinical Salmonella isolates resistant to these three antibiotics have been detected occasionally in recent years, but cotransfer of such three antimicrobial resistance determinants in one plasmid was rarely reported (4).

KW - Azithromycin

KW - Ceftriaxone

KW - Ciprofloxacin

KW - Conjugative plasmid

KW - IncC type

KW - Salmonella

UR - https://www.scopus.com/pages/publications/85112854651

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85112854651&origin=recordpage

U2 - 10.1128/AAC.01046-21

DO - 10.1128/AAC.01046-21

M3 - RGC 21 - Publication in refereed journal

C2 - 34125592

SN - 0066-4804

VL - 65

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 9

M1 - 01046

ER -

Emergence of conjugative IncC type plasmid simultaneously encoding resistance to ciprofloxacin, ceftriaxone and azithromycin in Salmonella

Abstract

Research Keywords

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RIF: Development of a Colistin/Adjuvant Antimicrobial Regimen That Exhibits Low Toxicity and High Efficacy in Combating Multi-drug-resistant Bacterial Pathogens

CRF: Development of Novel Inhibitors Targeting the Resistance Mechanisms of Clinical Superbugs

Cite this

Emergence of conjugative IncC type plasmid simultaneously encoding resistance to ciprofloxacin, ceftriaxone and azithromycin in Salmonella

Abstract

Research Keywords

RGC Funding Information

Access Output

Other Access Options

Permanent Link

Other Files and Links

Fingerprint

Projects

RIF: Development of a Colistin/Adjuvant Antimicrobial Regimen That Exhibits Low Toxicity and High Efficacy in Combating Multi-drug-resistant Bacterial Pathogens

CRF: Development of Novel Inhibitors Targeting the Resistance Mechanisms of Clinical Superbugs

Cite this