Emergence of Carbapenem-Resistant Serotype K1 Hypervirulent Klebsiella pneumoniae Strains in China

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Rong Zhang
  • Dachuan Lin
  • Edward Wai-Chi Chan
  • Danxia Gu
  • Gong-Xiang Chen

Detail(s)

Original languageEnglish
Pages (from-to)709-711
Journal / PublicationAntimicrobial Agents and Chemotherapy
Volume60
Issue number1
Online published31 Dec 2015
Publication statusPublished - Jan 2016
Externally publishedYes

Abstract

We report the emergence of five carbapenem-resistant K1 hypervirulent Klebsiella pneumoniae (hvKP) strains which caused fatal infections in hospital patients in Zhejiang Province, China, upon entry through surgical wounds. Genotyping results revealed the existence of three genetically related strains which exhibited a new sequence type, ST1797, and revealed that all strains harbored the magA and wcaG virulence genes and a plasmid-borne blaKPC-2 gene. These findings indicate that K1 hvKP is simultaneously hypervirulent, multidrug resistant, and transmissible.

Citation Format(s)

Emergence of Carbapenem-Resistant Serotype K1 Hypervirulent Klebsiella pneumoniae Strains in China. / Zhang, Rong; Lin, Dachuan; Chan, Edward Wai-Chi; Gu, Danxia; Chen, Gong-Xiang; Chen, Sheng.

In: Antimicrobial Agents and Chemotherapy, Vol. 60, No. 1, 01.2016, p. 709-711.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review