Electrochemical biosensing platforms on the basis of reduced graphene oxide and its composites with Au nanodots

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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Detail(s)

Original languageEnglish
Pages (from-to)3749-3756
Journal / PublicationAnalyst
Volume145
Issue number10
Online published20 Mar 2020
Publication statusPublished - 21 May 2020

Abstract

Reduced graphene oxide (rGO) and Au nanodot (AuND, ∼1.5 nm) modified rGO, referred to as AuNDsrGO, synthesized by a simple photochemical reduction method, are used for electrochemical biosensors. Our experimental results showed that the glucose oxidase (GOX)/rGO/Nafion/glassy carbon electrode (GCE) exhibits a linear range from 0.03 to 6.28 mM and a detection limit of 0.03 mM at a signal-to-noise (S/N) ratio of 3 for the amperometric sensing of glucose, while the GOX/AuNDs-rGO/Nafion/GCE shows a wider linear range from 0.02 to 8.82 mM and a lower detection limit of 0.02 mM. This difference may arise from the high catalytic activity of the AuNDs. Our studies demonstrate that the composites of rGO/ Nafion and AuNDs-rGO/Nafion might offer a new class of electrode materials, and provide a promising platform for biosensing applications.