TY - GEN
T1 - Effects of prolonged stimulation at the electrode-retina interface
AU - Ray, A.
AU - Chan, L.
AU - Thomas, B.
AU - Weiland, J. D.
PY - 2006
Y1 - 2006
N2 - Prolonged electrical stimulation can lead to temporary or permanent changes in neural response. Stimulation of neurons at levels sufficient to cause overlapping zones of excitation can induce multiple effects, leading to permanent damage to neurons or temporary depression not detectable through histopathological analysis. The present study focuses on determining the effects of prolonged, continuous electrical stimulation in the retina. One hour stimulation was performed in the rat retina and electrically evoked responses in the superior colliculus were recorded before and after the continuous stimulation. Comparison of the pre and post stimulation responses indicates a depression in the excitability of the neurons. © 2006 IEEE.
AB - Prolonged electrical stimulation can lead to temporary or permanent changes in neural response. Stimulation of neurons at levels sufficient to cause overlapping zones of excitation can induce multiple effects, leading to permanent damage to neurons or temporary depression not detectable through histopathological analysis. The present study focuses on determining the effects of prolonged, continuous electrical stimulation in the retina. One hour stimulation was performed in the rat retina and electrically evoked responses in the superior colliculus were recorded before and after the continuous stimulation. Comparison of the pre and post stimulation responses indicates a depression in the excitability of the neurons. © 2006 IEEE.
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UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-34047129249&origin=recordpage
U2 - 10.1109/IEMBS.2006.260805
DO - 10.1109/IEMBS.2006.260805
M3 - RGC 32 - Refereed conference paper (with host publication)
SN - 1424400325
SN - 9781424400324
SP - 1285
EP - 1287
BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
T2 - 28<sup>th</sup> Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS 2006)
Y2 - 30 August 2006 through 3 September 2006
ER -