Effects of organic toxicants on the anoxic energy metabolism of the mussel Mytilus edulis

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Original languageEnglish
Pages (from-to)327-331
Journal / PublicationMarine Environmental Research
Issue number1-4
Publication statusPublished - 1992
Externally publishedYes


Title6th International Symposium on Responses of Marine Organisms to Pollutants
PlaceUnited States
Period24 - 26 April 1991


The anoxic rates of heat dissipation by mussels (Mytilus edulis) were enhanced after exposure to pentachlorophenol (PCP) and tributyltin (TBT), both known uncouplers of oxidative phosphorylation. The degree of metabolic activation under anoxia was dependent upon the amount of toxicant accumulated in the tissues, but the concentration-response relationship was different to that under aerobic conditions. Biochemical measurements indicated that the anaerobic metabolic pathways were significantly disturbed by PCP and TBT. There was a decline in succinate, an increase in the fumarate: succinate ratio, and an increase in the accumulation of lactate, indicating a shift from succinate to lactate anaerobic pathways. A consequence of organic toxicant exposure was a reduction in anoxic survival time of mussels. © 1992.

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