Effects of exogenous carbon monoxide on radiation-induced bystander effect in zebrafish embryos in vivo

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Original languageEnglish
Pages (from-to)1075-1079
Journal / PublicationApplied Radiation and Isotopes
Issue number7
Publication statusPublished - Jul 2012


In the present work, the influence of a low concentration of exogenous carbon monoxide (CO) liberated from tricarbonylchloro(glycinato)ruthenium (II) (CORM-3) on the radiation induced bystander effect (RIBE) in vivo between embryos of the zebrafish was studied. RIBE was assessed through the number of apoptotic signals revealed on embryos at 25. h post fertilization (hpf). A significant attenuation of apoptosis on the bystander embryos induced by RIBE in a CO concentration dependent manner was observed. © 2011 Elsevier Ltd.

Research Area(s)

  • Alpha particles, Bystander effect, CO, CORM-3, Zebrafish embryos