Effects of dietary exposure to ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma)

Meng Yan; Maggie Y.L. Mak; Jinping Cheng; Jing Li; Jia Rui Gu; Priscilla T.Y. Leung; Paul K.S. Lam

doi:10.1016/j.marpolbul.2019.110837

Effects of dietary exposure to ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma)

Meng Yan^*
, Maggie Y.L. Mak
, Jinping Cheng
, Jing Li
, Jia Rui Gu
, Priscilla T.Y. Leung^*
, Paul K.S. Lam

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

26 Citations (Scopus)

Abstract

Ciguatoxins are natural compounds produced by benthic dinoflagellates Gambierdiscus and Fukuyoa spp., which cause fish intoxication by ciguatera fish poisoning. This study aimed to assess the dietary exposure effects of ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma). Fish which ingested >1.16 pg·day⁻¹ for 21 days exhibited abnormal behaviors including diarrhea, abnormal swimming, loss of appetite and decreased egg production. After 7-day exposure to P-CTX-1 at a dose of 1.93 pg·day⁻¹, significant gender-specific differences in reproductive performance and decreased hatching rate of the offspring were observed. Chemical analysis of P-CTX-1 showed that the P-CTX-1 accumulation rates were 24.1 ± 1.4% in female fish and 9.9 ± 0.4% in male fish, and 0.05 pg·egg⁻¹ was detected. The results illustrate that dietary exposure to P-CTX-1 affected the reproductive performance and survival of offspring, and caused bioaccumulation and maternal transfer of P-CTX-1 in marine medaka.

Original language	English
Article number	110837
Journal	Marine Pollution Bulletin
Volume	152
Online published	25 Jan 2020
DOIs	https://doi.org/10.1016/j.marpolbul.2019.110837
Publication status	Published - Mar 2020

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 14 Life Below Water

Research Keywords

Bio-encapsulation
Ciguatoxin
Gambierdiscus
Maternal transfer
Oryzias melastigma
Reproduction

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10.1016/j.marpolbul.2019.110837

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@article{9ee78ad849dd4e48a1248def202312cf,

title = "Effects of dietary exposure to ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma)",

abstract = "Ciguatoxins are natural compounds produced by benthic dinoflagellates Gambierdiscus and Fukuyoa spp., which cause fish intoxication by ciguatera fish poisoning. This study aimed to assess the dietary exposure effects of ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma). Fish which ingested >1.16 pg·day−1 for 21 days exhibited abnormal behaviors including diarrhea, abnormal swimming, loss of appetite and decreased egg production. After 7-day exposure to P-CTX-1 at a dose of 1.93 pg·day−1, significant gender-specific differences in reproductive performance and decreased hatching rate of the offspring were observed. Chemical analysis of P-CTX-1 showed that the P-CTX-1 accumulation rates were 24.1 ± 1.4\% in female fish and 9.9 ± 0.4\% in male fish, and 0.05 pg·egg−1 was detected. The results illustrate that dietary exposure to P-CTX-1 affected the reproductive performance and survival of offspring, and caused bioaccumulation and maternal transfer of P-CTX-1 in marine medaka.",

keywords = "Bio-encapsulation, Ciguatoxin, Gambierdiscus, Maternal transfer, Oryzias melastigma, Reproduction",

author = "Meng Yan and Mak, \{Maggie Y.L.\} and Jinping Cheng and Jing Li and Gu, \{Jia Rui\} and Leung, \{Priscilla T.Y.\} and Lam, \{Paul K.S.\}",

year = "2020",

month = mar,

doi = "10.1016/j.marpolbul.2019.110837",

language = "English",

volume = "152",

journal = "Marine Pollution Bulletin",

issn = "0025-326X",

publisher = "Elsevier Ltd.",

}

TY - JOUR

T1 - Effects of dietary exposure to ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma)

AU - Yan, Meng

AU - Mak, Maggie Y.L.

AU - Cheng, Jinping

AU - Li, Jing

AU - Gu, Jia Rui

AU - Leung, Priscilla T.Y.

AU - Lam, Paul K.S.

PY - 2020/3

Y1 - 2020/3

N2 - Ciguatoxins are natural compounds produced by benthic dinoflagellates Gambierdiscus and Fukuyoa spp., which cause fish intoxication by ciguatera fish poisoning. This study aimed to assess the dietary exposure effects of ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma). Fish which ingested >1.16 pg·day−1 for 21 days exhibited abnormal behaviors including diarrhea, abnormal swimming, loss of appetite and decreased egg production. After 7-day exposure to P-CTX-1 at a dose of 1.93 pg·day−1, significant gender-specific differences in reproductive performance and decreased hatching rate of the offspring were observed. Chemical analysis of P-CTX-1 showed that the P-CTX-1 accumulation rates were 24.1 ± 1.4% in female fish and 9.9 ± 0.4% in male fish, and 0.05 pg·egg−1 was detected. The results illustrate that dietary exposure to P-CTX-1 affected the reproductive performance and survival of offspring, and caused bioaccumulation and maternal transfer of P-CTX-1 in marine medaka.

AB - Ciguatoxins are natural compounds produced by benthic dinoflagellates Gambierdiscus and Fukuyoa spp., which cause fish intoxication by ciguatera fish poisoning. This study aimed to assess the dietary exposure effects of ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma). Fish which ingested >1.16 pg·day−1 for 21 days exhibited abnormal behaviors including diarrhea, abnormal swimming, loss of appetite and decreased egg production. After 7-day exposure to P-CTX-1 at a dose of 1.93 pg·day−1, significant gender-specific differences in reproductive performance and decreased hatching rate of the offspring were observed. Chemical analysis of P-CTX-1 showed that the P-CTX-1 accumulation rates were 24.1 ± 1.4% in female fish and 9.9 ± 0.4% in male fish, and 0.05 pg·egg−1 was detected. The results illustrate that dietary exposure to P-CTX-1 affected the reproductive performance and survival of offspring, and caused bioaccumulation and maternal transfer of P-CTX-1 in marine medaka.

KW - Bio-encapsulation

KW - Ciguatoxin

KW - Gambierdiscus

KW - Maternal transfer

KW - Oryzias melastigma

KW - Reproduction

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UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85078170984&origin=recordpage

U2 - 10.1016/j.marpolbul.2019.110837

DO - 10.1016/j.marpolbul.2019.110837

M3 - RGC 21 - Publication in refereed journal

SN - 0025-326X

VL - 152

JO - Marine Pollution Bulletin

JF - Marine Pollution Bulletin

M1 - 110837

ER -

Effects of dietary exposure to ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma)

Abstract

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CRF: Benthic and Epiphytic Toxic Algae (BETA): An Emerging Threat to Coral Ecosystems in Hong Kong Waters

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Effects of dietary exposure to ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma)

Abstract

UN SDGs

Research Keywords

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Projects

CRF: Benthic and Epiphytic Toxic Algae (BETA): An Emerging Threat to Coral Ecosystems in Hong Kong Waters

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