Effects of alpha particles on zebrafish embryos

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

29 Scopus Citations
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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)714-717
Journal / PublicationApplied Radiation and Isotopes
Volume68
Issue number4-5
Publication statusPublished - Apr 2010

Abstract

Dechorionated zebrafish embryos were irradiated at 1.5 h post fertilization (hpf) to low-doses of alpha particles, viz., 1.4, 2.8, 5.6, 11.2 mGy (determined using Monte Carlo simulations). At 24 hpf, these embryos were then examined for apoptotic cells through acridine orange staining. The mean number of apoptotic cells was found to decrease significantly from controls to 1.4-mGy irradiation, and then to increase almost linearly to 2.8, 5.6 and 11.2-mGy irradiation. This trend is a typical characteristic of a hormetic effect. © 2009 Elsevier Ltd. All rights reserved.

Research Area(s)

  • Alpha particles, Hormetic effect, Radiation hormesis, Zebrafish embryos