Effects of Acceptance and Commitment Therapy on fatigue interference and health-related quality of life among patients with advanced lung cancer: A pilot randomized controlled trial

Huiyuan Li, Xiaohuan Jin, Marques Shek Nam Ng, Ka Fai Mann, Nina Wang, Cho Lee Wong*

*Corresponding author for this work

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

27 Citations (Scopus)
128 Downloads (CityUHK Scholars)

Abstract

Objective: The present study aimed to examine the feasibility and preliminary effects of Acceptance and Commitment Therapy (ACT) on fatigue interference and health-related quality of life in patients with advanced lung cancer. Methods: In a single-blinded, parallel-group randomized controlled trial, 40 patients with advanced lung cancer were randomized to either the intervention group, which received the four-session individual ACT in 4 weeks, or the control group, which received usual care. The outcomes were evaluated at baseline and one week postintervention. Results: Intervention feasibility and acceptability were established with a high attendance rate of 88.75% and a high retention rate of 75%. Approximately 95% of the participants reported satisfaction with the intervention. Despite the insignificant effects on fatigue interference, statistically significant interactions effects of ACT for health-related quality of life (P ​= ​0.001), cancer-related fatigue (P ​< ​0.001), depressive symptoms (P ​< ​0.001), anxiety (P ​< ​0.001), and distress (P ​= ​0.003) were noted. Conclusions: This pilot trial supports the feasibility and acceptability of conducting ACT for patients with advanced lung cancer. The findings show the potential positive effects of ACT on health-related quality of life. Future studies with full-scale samples are recommended to evaluate the long-term effects of ACT on fatigue interference.
Original languageEnglish
Article number100102
JournalAsia-Pacific Journal of Oncology Nursing
Volume9
Issue number8
Online published9 Jun 2022
DOIs
Publication statusPublished - Aug 2022

Research Keywords

  • Acceptance and Commitment Therapy
  • Fatigue
  • Health-related quality of life
  • Lung cancer

Publisher's Copyright Statement

  • This full text is made available under CC-BY-NC-ND 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/

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