Abstract
Background: To evaluate and compare the effectiveness of four types of non-pharmaceutical interventions (NPIs) to contain the time-varying effective reproduction number (Rt) of coronavirus disease-2019 (COVID-19).
Methods: This study included 1,908,197 confirmed COVID-19 cases from 190 countries between 23 January and 13 April 2020. The implemented NPIs were categorised into four types: mandatory face mask in public, isolation or quarantine, social distancing and traffic restriction (referred to as mandatory mask, quarantine, distancing and traffic hereafter, respectively).
Results: The implementations of mandatory mask, quarantine, distancing and traffic were associated with changes (95% confidence interval, CI) of −15.14% (from −21.79% to −7.93%), −11.40% (from −13.66% to −9.07%), −42.94% (from −44.24% to −41.60%) and −9.26% (from −11.46% to −7.01%) in the Rt of COVID-19 when compared with those without the implementation of the corresponding measures. Distancing and the simultaneous implementation of two or more types of NPIs seemed to be associated with a greater decrease in the Rt of COVID-19.
Conclusion: Our study indicates that NPIs can significantly contain the COVID-19 pandemic. Distancing and the simultaneous implementation of two or more NPIs should be the strategic priorities for containing COVID-19.
© 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
Methods: This study included 1,908,197 confirmed COVID-19 cases from 190 countries between 23 January and 13 April 2020. The implemented NPIs were categorised into four types: mandatory face mask in public, isolation or quarantine, social distancing and traffic restriction (referred to as mandatory mask, quarantine, distancing and traffic hereafter, respectively).
Results: The implementations of mandatory mask, quarantine, distancing and traffic were associated with changes (95% confidence interval, CI) of −15.14% (from −21.79% to −7.93%), −11.40% (from −13.66% to −9.07%), −42.94% (from −44.24% to −41.60%) and −9.26% (from −11.46% to −7.01%) in the Rt of COVID-19 when compared with those without the implementation of the corresponding measures. Distancing and the simultaneous implementation of two or more types of NPIs seemed to be associated with a greater decrease in the Rt of COVID-19.
Conclusion: Our study indicates that NPIs can significantly contain the COVID-19 pandemic. Distancing and the simultaneous implementation of two or more NPIs should be the strategic priorities for containing COVID-19.
© 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
| Original language | English |
|---|---|
| Pages (from-to) | 247-253 |
| Number of pages | 7 |
| Journal | International Journal of Infectious Diseases |
| Volume | 102 |
| Online published | 29 Oct 2020 |
| DOIs | |
| Publication status | Published - Jan 2021 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2020 The Authors
Funding
This study is in part supported by the Environmental Health Research Fund of the Chinese University of Hong Kong (7104946). Yacong Bo is supported by the Ph.D. Studentship of the Chinese University of Hong Kong. This study is in part supported by the E nvironmental Health Research Fund of the C hinese University of Hong Kong ( 7104946) . Yacong Bo is supported by the Ph.D. Studentship of the Chinese University of Hong Kong.
Research Keywords
- COVID-19
- Non-pharmaceutical interventions
- Time-Varying effective reproduction number (Rt)
Publisher's Copyright Statement
- This full text is made available under CC-BY-NC-ND 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/
Policy Impact
- Cited in Policy Documents
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