Effect-directed analysis and mixture effects of AhR-active PAHs in crude oil and coastal sediments contaminated by the Hebei Spirit oil spill

Seongjin Hong; Sangwoo Lee; Kyungho Choi; Gi Beum Kim; Sung Yong Ha; Bong-Oh Kwon; Jongseong Ryu; Un Hyuk Yim; Won Joon Shim; Jinho Jung; John P. Giesy; Jong Seong Khim

doi:10.1016/j.envpol.2015.01.009

Effect-directed analysis and mixture effects of AhR-active PAHs in crude oil and coastal sediments contaminated by the Hebei Spirit oil spill

Seongjin Hong, Sangwoo Lee, Kyungho Choi, Gi Beum Kim, Sung Yong Ha, Bong-Oh Kwon, Jongseong Ryu, Un Hyuk Yim, Won Joon Shim, Jinho Jung, John P. Giesy, Jong Seong Khim^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

44 Citations (Scopus)

Abstract

The major AhR-active PAHs were identified in crude oil and oil-contaminated sediments by use of effect-directed analysis. As part of the study, an enhanced potency balance analysis was conducted by establishing the novel relative potency values of (alkyl)-PAHs from the H4IIE-luc bioassay. Silica gel column fractionation of crude oil resulted in greater AhR-mediated potencies in fractions of aromatics (F2) and resins (F3), and such trend was also observed for field collected sediment samples. AhR-mediated potencies of six F2 sub-fractions from HPLC indicated that the majority of F2 responses were attributable to 3-4 ring aromatics. Target PAHs including C4-phenanthrene, C1-chrysene, and C3-chrysene in sediments explained ∼18% of the bioassay-derived TCDD-EQs, however, the unknown AhR agonists and potential mixture effects remain in question. Overall, the AhR-potency and antagonistic potential of residual oil in sediment tended to decrease over time, thus monitoring of weathering process would be key for the post management of oil-contaminated sites.

Original language	English
Pages (from-to)	110-118
Journal	Environmental Pollution
Volume	199
DOIs	https://doi.org/10.1016/j.envpol.2015.01.009
Publication status	Published - Apr 2015

Research Keywords

Effect-directed analysis
H4IIE-luc bioassay
Oil weathering
Polycyclic aromatic hydrocarbons
Sediments
Yellow Sea

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Hong, S., Lee, S., Choi, K., Kim, G. B., Ha, S. Y., Kwon, B.-O., Ryu, J., Yim, U. H., Shim, W. J., Jung, J., Giesy, J. P., & Khim, J. S. (2015). Effect-directed analysis and mixture effects of AhR-active PAHs in crude oil and coastal sediments contaminated by the Hebei Spirit oil spill. Environmental Pollution, 199, 110-118. https://doi.org/10.1016/j.envpol.2015.01.009

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title = "Effect-directed analysis and mixture effects of AhR-active PAHs in crude oil and coastal sediments contaminated by the Hebei Spirit oil spill",

abstract = "The major AhR-active PAHs were identified in crude oil and oil-contaminated sediments by use of effect-directed analysis. As part of the study, an enhanced potency balance analysis was conducted by establishing the novel relative potency values of (alkyl)-PAHs from the H4IIE-luc bioassay. Silica gel column fractionation of crude oil resulted in greater AhR-mediated potencies in fractions of aromatics (F2) and resins (F3), and such trend was also observed for field collected sediment samples. AhR-mediated potencies of six F2 sub-fractions from HPLC indicated that the majority of F2 responses were attributable to 3-4 ring aromatics. Target PAHs including C4-phenanthrene, C1-chrysene, and C3-chrysene in sediments explained ∼18% of the bioassay-derived TCDD-EQs, however, the unknown AhR agonists and potential mixture effects remain in question. Overall, the AhR-potency and antagonistic potential of residual oil in sediment tended to decrease over time, thus monitoring of weathering process would be key for the post management of oil-contaminated sites.",

keywords = "Effect-directed analysis, H4IIE-luc bioassay, Oil weathering, Polycyclic aromatic hydrocarbons, Sediments, Yellow Sea",

author = "Seongjin Hong and Sangwoo Lee and Kyungho Choi and Kim, {Gi Beum} and Ha, {Sung Yong} and Bong-Oh Kwon and Jongseong Ryu and Yim, {Un Hyuk} and Shim, {Won Joon} and Jinho Jung and Giesy, {John P.} and Khim, {Jong Seong}",

year = "2015",

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doi = "10.1016/j.envpol.2015.01.009",

language = "English",

volume = "199",

pages = "110--118",

journal = "Environmental Pollution",

issn = "0013-9327",

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T1 - Effect-directed analysis and mixture effects of AhR-active PAHs in crude oil and coastal sediments contaminated by the Hebei Spirit oil spill

AU - Hong, Seongjin

AU - Lee, Sangwoo

AU - Choi, Kyungho

AU - Kim, Gi Beum

AU - Ha, Sung Yong

AU - Kwon, Bong-Oh

AU - Ryu, Jongseong

AU - Yim, Un Hyuk

AU - Shim, Won Joon

AU - Jung, Jinho

AU - Giesy, John P.

AU - Khim, Jong Seong

PY - 2015/4

Y1 - 2015/4

N2 - The major AhR-active PAHs were identified in crude oil and oil-contaminated sediments by use of effect-directed analysis. As part of the study, an enhanced potency balance analysis was conducted by establishing the novel relative potency values of (alkyl)-PAHs from the H4IIE-luc bioassay. Silica gel column fractionation of crude oil resulted in greater AhR-mediated potencies in fractions of aromatics (F2) and resins (F3), and such trend was also observed for field collected sediment samples. AhR-mediated potencies of six F2 sub-fractions from HPLC indicated that the majority of F2 responses were attributable to 3-4 ring aromatics. Target PAHs including C4-phenanthrene, C1-chrysene, and C3-chrysene in sediments explained ∼18% of the bioassay-derived TCDD-EQs, however, the unknown AhR agonists and potential mixture effects remain in question. Overall, the AhR-potency and antagonistic potential of residual oil in sediment tended to decrease over time, thus monitoring of weathering process would be key for the post management of oil-contaminated sites.

AB - The major AhR-active PAHs were identified in crude oil and oil-contaminated sediments by use of effect-directed analysis. As part of the study, an enhanced potency balance analysis was conducted by establishing the novel relative potency values of (alkyl)-PAHs from the H4IIE-luc bioassay. Silica gel column fractionation of crude oil resulted in greater AhR-mediated potencies in fractions of aromatics (F2) and resins (F3), and such trend was also observed for field collected sediment samples. AhR-mediated potencies of six F2 sub-fractions from HPLC indicated that the majority of F2 responses were attributable to 3-4 ring aromatics. Target PAHs including C4-phenanthrene, C1-chrysene, and C3-chrysene in sediments explained ∼18% of the bioassay-derived TCDD-EQs, however, the unknown AhR agonists and potential mixture effects remain in question. Overall, the AhR-potency and antagonistic potential of residual oil in sediment tended to decrease over time, thus monitoring of weathering process would be key for the post management of oil-contaminated sites.

KW - Effect-directed analysis

KW - H4IIE-luc bioassay

KW - Oil weathering

KW - Polycyclic aromatic hydrocarbons

KW - Sediments

KW - Yellow Sea

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U2 - 10.1016/j.envpol.2015.01.009

DO - 10.1016/j.envpol.2015.01.009

M3 - RGC 21 - Publication in refereed journal

C2 - 25645060

SN - 0013-9327

VL - 199

SP - 110

EP - 118

JO - Environmental Pollution

JF - Environmental Pollution

ER -

Effect-directed analysis and mixture effects of AhR-active PAHs in crude oil and coastal sediments contaminated by the Hebei Spirit oil spill

Abstract

Research Keywords

UN SDGs

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