EBV-associated synovial lymphoma in a chronically inflamed joint in rheumatoid arthritis receiving prolonged methotrexate treatment.

C. S. Chim, Y. Y. Pang, G. C. Ooi, M. Y. Mok, T. W. Shek

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

7 Citations (Scopus)

Abstract

A patient with longstanding rheumatoid arthritis (RA) developed swelling in a chronically inflamed knee joint while receiving prolonged methotrexate treatment. Magnetic resonance imaging and positron-emission tomography showed soft tissue swelling with intense tracer uptake. Biopsy confirmed high-grade B-cell lymphoma. He developed complete remission with rituximab plus CEOP. The role of chronic inflammation and methotrexate in the pathogenesis of lymphoma in RA was discussed.
Original languageEnglish
JournalHaematologica.
Volume91
Issue number8 Suppl
Publication statusPublished - Aug 2006
Externally publishedYes

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