Dual-emissive Iridium(III) Complexes as Phosphorescent Probes with Orthogonal Responses to Analyte Binding and Oxygen Quenching

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Rongji Zhu
  • Peiling Dai
  • Jun Yang
  • Jie Zhou
  • Jin Zhang
  • Kenneth Yin Zhang
  • Yonghua Li
  • Shujuan Liu
  • Qiang Zhao

Related Research Unit(s)

Detail(s)

Original languageEnglish
Article numbere202309178
Journal / PublicationAngewandte Chemie - International Edition
Volume62
Issue number37
Online published28 Jul 2023
Publication statusPublished - 11 Sept 2023

Abstract

Phosphorescent probes often show sensitive response toward analytes at a specific wavelength. However, oxygen quenching usually occurs at the same wavelength and thus hinders the accurate detection of analytes. In this study, we have developed dual-emissive iridium(III) complexes that exhibit phosphorescence responses to copper(II) ions at a wavelength distinct from that where oxygen quenching occurs. The complexes displayed colorimetric phosphorescence response in aqueous solutions under different copper(II) and oxygen conditions. In cellular imaging, variation in oxygen concentration over a large range from 5 % to 80 % can modulate the intensity and lifetime of green phosphorescence without affecting the response of red phosphorescence toward intracellular copper(II) ions. © 2023 Wiley-VCH GmbH.

Research Area(s)

  • Bioimaging, Dual-Emission, Iridium, Phosphorescence, Probes

Citation Format(s)

Dual-emissive Iridium(III) Complexes as Phosphorescent Probes with Orthogonal Responses to Analyte Binding and Oxygen Quenching. / Zhu, Rongji; Dai, Peiling; Yang, Jun et al.
In: Angewandte Chemie - International Edition, Vol. 62, No. 37, e202309178, 11.09.2023.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review