Double emulsion templated monodisperse phospholipid vesicles

Ho Cheung Shum; Daeyeon Lee; Insun Yoon; Tom Kodger; David A. Weitz

doi:10.1021/la801833a

Double emulsion templated monodisperse phospholipid vesicles

Ho Cheung Shum
, Daeyeon Lee
, Insun Yoon
, Tom Kodger
, David A. Weitz

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

324 Citations (Scopus)

Abstract

We present a novel approach for fabricating monodisperse phospholipid vesicles with high encapsulation efficiency using controlled double emulsions as templates. Glass-capillary microfluidics is used to generate monodisperse double emulsion templates. We show that the high uniformity in size and shape of the templates are maintained in the final phospholipid vesicles after a solvent removal step. Our simple and versatile technique is applicable to a wide range of phospholipids. © 2008 American Chemical Society.

Original language	English
Pages (from-to)	7651-7653
Journal	Langmuir
Volume	24
Issue number	15
DOIs	https://doi.org/10.1021/la801833a
Publication status	Published - 5 Aug 2008
Externally published	Yes

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Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

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title = "Double emulsion templated monodisperse phospholipid vesicles",

abstract = "We present a novel approach for fabricating monodisperse phospholipid vesicles with high encapsulation efficiency using controlled double emulsions as templates. Glass-capillary microfluidics is used to generate monodisperse double emulsion templates. We show that the high uniformity in size and shape of the templates are maintained in the final phospholipid vesicles after a solvent removal step. Our simple and versatile technique is applicable to a wide range of phospholipids. {\textcopyright} 2008 American Chemical Society.",

author = "Shum, \{Ho Cheung\} and Daeyeon Lee and Insun Yoon and Tom Kodger and Weitz, \{David A.\}",

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T1 - Double emulsion templated monodisperse phospholipid vesicles

AU - Shum, Ho Cheung

AU - Lee, Daeyeon

AU - Yoon, Insun

AU - Kodger, Tom

AU - Weitz, David A.

N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

PY - 2008/8/5

Y1 - 2008/8/5

N2 - We present a novel approach for fabricating monodisperse phospholipid vesicles with high encapsulation efficiency using controlled double emulsions as templates. Glass-capillary microfluidics is used to generate monodisperse double emulsion templates. We show that the high uniformity in size and shape of the templates are maintained in the final phospholipid vesicles after a solvent removal step. Our simple and versatile technique is applicable to a wide range of phospholipids. © 2008 American Chemical Society.

AB - We present a novel approach for fabricating monodisperse phospholipid vesicles with high encapsulation efficiency using controlled double emulsions as templates. Glass-capillary microfluidics is used to generate monodisperse double emulsion templates. We show that the high uniformity in size and shape of the templates are maintained in the final phospholipid vesicles after a solvent removal step. Our simple and versatile technique is applicable to a wide range of phospholipids. © 2008 American Chemical Society.

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DO - 10.1021/la801833a

M3 - RGC 21 - Publication in refereed journal

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VL - 24

SP - 7651

EP - 7653

JO - Langmuir

JF - Langmuir

IS - 15

ER -

Double emulsion templated monodisperse phospholipid vesicles

Abstract

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