Dosimetric study of radioadaptive response of zebrafish embryos using PADC-film substrates

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Detail(s)

Original languageEnglish
Pages (from-to)1795-1798
Journal / PublicationRadiation Measurements
Volume46
Issue number12
Publication statusPublished - Dec 2011

Abstract

We found the alpha-particle priming dose which could effectively induce in vivo radioadaptive response in the embryos of the zebrafish, Danio rerio, to be 4.8-48 μGy, through the apoptotic signals scored in the embryos at 24 h post fertilization. Specially fabricated thin polyallyldiglycol carbonate (PADC) films were used as support substrates for the dechorionated embryos. During irradiation, alpha particles passed through the PADC films to hit the zebrafish embryos, and the alpha-particle tracks were revealed in the films through chemical etching. By determining the number of alpha-particle tracks that coincided with the effective areas of the embryos, the alpha-particle doses were found. © 2011 Elsevier Ltd. All rights reserved.

Research Area(s)

  • Adaptive response, Alpha particles, CR-39, PADC, Zebrafish embryos

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