DNA-Templated Silver Nanoclusters for Multiplexed Fluorescent DNA Detection

Ying Zhang; Changfeng Zhu; Lei Zhang; Chaoliang Tan; Jian Yang; Bo Chen; Lianhui Wang; Hua Zhang

doi:10.1002/smll.201402044

DNA-Templated Silver Nanoclusters for Multiplexed Fluorescent DNA Detection

Ying Zhang
, Changfeng Zhu
, Lei Zhang
, Chaoliang Tan
, Jian Yang
, Bo Chen
, Lianhui Wang^*
, Hua Zhang^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

114 Citations (Scopus)

Abstract

Novel label-free/conjugation-free molecular beacons are designed based on DNA templated-silver nanoclusters for multiplexed DNA detection. The assay is implemented in solution, which makes it easy for the in-situ and real-time analysis. This study demonstrates a new method for multiplexd detection of biological molecules by using fluorescent Ag nanocluster-based molecular beacon probes.

Original language	English
Pages (from-to)	1385-1389
Journal	Small
Volume	11
Issue number	12
Online published	10 Dec 2014
DOIs	https://doi.org/10.1002/smll.201402044
Publication status	Published - 25 Mar 2015
Externally published	Yes

Research Keywords

DNA
fluorescence
multiplexed detection
sensors
silver nanoclusters

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10.1002/smll.201402044

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title = "DNA-Templated Silver Nanoclusters for Multiplexed Fluorescent DNA Detection",

abstract = "Novel label-free/conjugation-free molecular beacons are designed based on DNA templated-silver nanoclusters for multiplexed DNA detection. The assay is implemented in solution, which makes it easy for the in-situ and real-time analysis. This study demonstrates a new method for multiplexd detection of biological molecules by using fluorescent Ag nanocluster-based molecular beacon probes.",

keywords = "DNA, fluorescence, multiplexed detection, sensors, silver nanoclusters",

author = "Ying Zhang and Changfeng Zhu and Lei Zhang and Chaoliang Tan and Jian Yang and Bo Chen and Lianhui Wang and Hua Zhang",

year = "2015",

month = mar,

day = "25",

doi = "10.1002/smll.201402044",

language = "English",

volume = "11",

pages = "1385--1389",

journal = "Small",

issn = "1613-6810",

publisher = "Wiley-VCH Verlag GmbH",

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}

TY - JOUR

T1 - DNA-Templated Silver Nanoclusters for Multiplexed Fluorescent DNA Detection

AU - Zhang, Ying

AU - Zhu, Changfeng

AU - Zhang, Lei

AU - Tan, Chaoliang

AU - Yang, Jian

AU - Chen, Bo

AU - Wang, Lianhui

AU - Zhang, Hua

PY - 2015/3/25

Y1 - 2015/3/25

N2 - Novel label-free/conjugation-free molecular beacons are designed based on DNA templated-silver nanoclusters for multiplexed DNA detection. The assay is implemented in solution, which makes it easy for the in-situ and real-time analysis. This study demonstrates a new method for multiplexd detection of biological molecules by using fluorescent Ag nanocluster-based molecular beacon probes.

AB - Novel label-free/conjugation-free molecular beacons are designed based on DNA templated-silver nanoclusters for multiplexed DNA detection. The assay is implemented in solution, which makes it easy for the in-situ and real-time analysis. This study demonstrates a new method for multiplexd detection of biological molecules by using fluorescent Ag nanocluster-based molecular beacon probes.

KW - DNA

KW - fluorescence

KW - multiplexed detection

KW - sensors

KW - silver nanoclusters

UR - https://www.scopus.com/pages/publications/84925039632

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84925039632&origin=recordpage

U2 - 10.1002/smll.201402044

DO - 10.1002/smll.201402044

M3 - RGC 21 - Publication in refereed journal

C2 - 25491417

SN - 1613-6810

VL - 11

SP - 1385

EP - 1389

JO - Small

JF - Small

IS - 12

ER -

DNA-Templated Silver Nanoclusters for Multiplexed Fluorescent DNA Detection

Abstract

Research Keywords

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