Dissemination of IncI2 Plasmids That Harbor the blaCTX-M Element among Clinical Salmonella Isolates

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

18 Scopus Citations
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Author(s)

  • Marcus Ho-Yin Wong
  • Lizhang Liu
  • Meiying Yan
  • Edward Wai-Chi Chan
  • Sheng Chen

Detail(s)

Original languageEnglish
Pages (from-to)5026-5028
Journal / PublicationAntimicrobial Agents and Chemotherapy
Volume59
Issue number8
Online published16 Jul 2015
Publication statusPublished - 1 Aug 2015
Externally publishedYes

Abstract

The extended-spectrum-β-lactamase (ESBL) determinant CTX-M-55 is increasingly prevalent in Escherichia coli but remains extremely rare in Salmonella. This study reports the isolation of a plasmid harboring the blaCTX-M-55 element in a clinical Salmonella enterica serotype Typhimurium strain resistant to multiple antibiotics. This plasmid is genetically identical to several known IncI2-type elements harbored by E. coli strains recovered from animals. This finding indicates that IncI2 plasmids harboring the blaCTX-M genes may undergo cross-species migration among potential bacterial pathogens, with E. coli as the major source of such elements.

Citation Format(s)

Dissemination of IncI2 Plasmids That Harbor the blaCTX-M Element among Clinical Salmonella Isolates. / Wong, Marcus Ho-Yin; Liu, Lizhang; Yan, Meiying; Chan, Edward Wai-Chi; Chen, Sheng.

In: Antimicrobial Agents and Chemotherapy, Vol. 59, No. 8, 01.08.2015, p. 5026-5028.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review