Disinfection by hydrogen peroxide nebulization increases susceptibility to avian pathogenic Escherichia coli

Leon H. Oosterik; Huruma N. Tuntufye; Steven Janssens; Patrick Butaye; Bruno M. Goddeeris

doi:10.1186/s13104-015-1329-z

Disinfection by hydrogen peroxide nebulization increases susceptibility to avian pathogenic Escherichia coli

Leon H. Oosterik^*
, Huruma N. Tuntufye
, Steven Janssens
, Patrick Butaye
, Bruno M. Goddeeris

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

3 Citations (Scopus)

Abstract

Background: Avian pathogenic Escherichia coli (APEC) are the major cause of economic losses in the poultry industry worldwide. Traditionally, antibiotics are used to treat and prevent colibacillosis in broilers. Due to resistance development other ways of preventing/treating the disease have to be found. Therefore during this study the nebulization of low concentrations of hydrogen peroxide (H₂O₂) was tested in the presence of chickens to lower pathogenicity of APEC. Results: Significantly higher total lesion scores and higher E. coli concentrations were found in the spleen of chickens exposed to 2 % H₂O₂ compared to those exposed to 1 % H₂O₂ and control chickens which had been exposed to nebulization with distilled water. Higher total lesions scores and E. coli concentrations in the spleen were found in chickens exposed to 1 % H₂O₂ in comparison to control chickens (not significant). Conclusion: H₂O₂ is rendering animals more prone to APEC infection contraindicating H₂O₂ nebulization in the presence of chickens. © 2015 Oosterik et al.

Original language	English
Article number	378
Journal	BMC Research Notes
Volume	8
Issue number	1
DOIs	https://doi.org/10.1186/s13104-015-1329-z
Publication status	Published - 27 Aug 2015
Externally published	Yes

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Funding

We thank Jessica Tsonos and Tom Luyten for their assistance. This study was funded by the Belgian Federal Public Service of Health, Food Chain Safety and Environment (contract RT 09/8 APECON) and by CODA-CERVA (contract APEC-BED).

Research Keywords

Avian pathogenic Escherichia coli
Disinfection
Hydrogen peroxide

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title = "Disinfection by hydrogen peroxide nebulization increases susceptibility to avian pathogenic Escherichia coli",

abstract = "Background: Avian pathogenic Escherichia coli (APEC) are the major cause of economic losses in the poultry industry worldwide. Traditionally, antibiotics are used to treat and prevent colibacillosis in broilers. Due to resistance development other ways of preventing/treating the disease have to be found. Therefore during this study the nebulization of low concentrations of hydrogen peroxide (H2O2) was tested in the presence of chickens to lower pathogenicity of APEC. Results: Significantly higher total lesion scores and higher E. coli concentrations were found in the spleen of chickens exposed to 2 \% H2O2 compared to those exposed to 1 \% H2O2 and control chickens which had been exposed to nebulization with distilled water. Higher total lesions scores and E. coli concentrations in the spleen were found in chickens exposed to 1 \% H2O2 in comparison to control chickens (not significant). Conclusion: H2O2 is rendering animals more prone to APEC infection contraindicating H2O2 nebulization in the presence of chickens. {\textcopyright} 2015 Oosterik et al.",

keywords = "Avian pathogenic Escherichia coli, Disinfection, Hydrogen peroxide",

author = "Oosterik, \{Leon H.\} and Tuntufye, \{Huruma N.\} and Steven Janssens and Patrick Butaye and Goddeeris, \{Bruno M.\}",

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AU - Oosterik, Leon H.

AU - Tuntufye, Huruma N.

AU - Janssens, Steven

AU - Butaye, Patrick

AU - Goddeeris, Bruno M.

N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

PY - 2015/8/27

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N2 - Background: Avian pathogenic Escherichia coli (APEC) are the major cause of economic losses in the poultry industry worldwide. Traditionally, antibiotics are used to treat and prevent colibacillosis in broilers. Due to resistance development other ways of preventing/treating the disease have to be found. Therefore during this study the nebulization of low concentrations of hydrogen peroxide (H2O2) was tested in the presence of chickens to lower pathogenicity of APEC. Results: Significantly higher total lesion scores and higher E. coli concentrations were found in the spleen of chickens exposed to 2 % H2O2 compared to those exposed to 1 % H2O2 and control chickens which had been exposed to nebulization with distilled water. Higher total lesions scores and E. coli concentrations in the spleen were found in chickens exposed to 1 % H2O2 in comparison to control chickens (not significant). Conclusion: H2O2 is rendering animals more prone to APEC infection contraindicating H2O2 nebulization in the presence of chickens. © 2015 Oosterik et al.

AB - Background: Avian pathogenic Escherichia coli (APEC) are the major cause of economic losses in the poultry industry worldwide. Traditionally, antibiotics are used to treat and prevent colibacillosis in broilers. Due to resistance development other ways of preventing/treating the disease have to be found. Therefore during this study the nebulization of low concentrations of hydrogen peroxide (H2O2) was tested in the presence of chickens to lower pathogenicity of APEC. Results: Significantly higher total lesion scores and higher E. coli concentrations were found in the spleen of chickens exposed to 2 % H2O2 compared to those exposed to 1 % H2O2 and control chickens which had been exposed to nebulization with distilled water. Higher total lesions scores and E. coli concentrations in the spleen were found in chickens exposed to 1 % H2O2 in comparison to control chickens (not significant). Conclusion: H2O2 is rendering animals more prone to APEC infection contraindicating H2O2 nebulization in the presence of chickens. © 2015 Oosterik et al.

KW - Avian pathogenic Escherichia coli

KW - Disinfection

KW - Hydrogen peroxide

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DO - 10.1186/s13104-015-1329-z

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Disinfection by hydrogen peroxide nebulization increases susceptibility to avian pathogenic Escherichia coli

Abstract

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