Direct Catalytic Hydrogenation of Simple Amides: A Highly Efficient Approach from Amides to Amines and Alcohols

Liyang Shi; Xuefeng Tan; Jiao Long; Xiong Xiong; Song Yang; Peng Xue; Hui Lv; Xumu Zhang

doi:10.1002/chem.201604904

Direct Catalytic Hydrogenation of Simple Amides: A Highly Efficient Approach from Amides to Amines and Alcohols

Liyang Shi, Xuefeng Tan, Jiao Long, Xiong Xiong, Song Yang, Peng Xue, Hui Lv^*, Xumu Zhang

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

56 Citations (Scopus)

Abstract

A highly chemoselective and reactive direct catalytic reduction of various amides to amines and alcohols was developed by using a tetradentate ruthenium complex. The catalytic system showed excellent activity (turnover numbers up to 19 600) and great functional group tolerance under mild reaction conditions, compared to several bidentate and tridentate ruthenium-catalyzed systems. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

Original language	English
Pages (from-to)	546-548
Journal	Chemistry - A European Journal
Volume	23
Issue number	3
DOIs	https://doi.org/10.1002/chem.201604904
Publication status	Published - 12 Jan 2017
Externally published	Yes

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Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Research Keywords

alcohols
amides
amines
chemoselectivity
hydrogenation

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AU - Shi, Liyang

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AU - Long, Jiao

AU - Xiong, Xiong

AU - Yang, Song

AU - Xue, Peng

AU - Lv, Hui

AU - Zhang, Xumu

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KW - alcohols

KW - amides

KW - amines

KW - chemoselectivity

KW - hydrogenation

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JF - Chemistry - A European Journal

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Direct Catalytic Hydrogenation of Simple Amides: A Highly Efficient Approach from Amides to Amines and Alcohols

Abstract

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