Dicobalt hexacarbonyl derivatives of chiral acetylenes

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • Márton Kajtár
  • Judit Kajtár-Miklós
  • Giampaolo Giacomelli
  • György Gaál
  • Gyul Váradi
  • Claudia Zucchi
  • Gyula Pályi

Detail(s)

Original languageEnglish
Pages (from-to)2177-2194
Journal / PublicationTetrahedron: Asymmetry
Volume6
Issue number9
Publication statusPublished - Sept 1995
Externally publishedYes

Abstract

2-RC2R′)Co2(CO)6 complexes are prepared where R ≠ R′ and one of these substituents is a chiral organic group. The structures of the 11 complexes (10 new) range from the simplest possible chiral acetylenic hydrocarbon derivative (S-3-methyl-1-pentyne 1a) to ethynylsteroid (1f, 1g, 1h) and ethynylcodeine (1i, 1j, 1k) derivatives. The CD spectra are reported and the results are analysed in terms of a quadrant rule. The CD spectra show that in all complexes the Co2(CO)6 fragment of the molecule gets chirally perturbed. The reasons for the chiral perturbation include apolar repulsing (dominant for the hydrocarbon acetylenes) and polar attractive ("autosolvation"; dominant for acetylenes with polar hetero-atom containing substituents) forces. © 1995.

Citation Format(s)

Dicobalt hexacarbonyl derivatives of chiral acetylenes. / Kajtár, Márton; Kajtár-Miklós, Judit; Giacomelli, Giampaolo et al.
In: Tetrahedron: Asymmetry, Vol. 6, No. 9, 09.1995, p. 2177-2194.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review