Development of automated patch clamp system for electrophysiology

Runhuai Yang; King W.C. Lai; Ning Xi; Jie Yang

doi:10.1109/ROBIO.2013.6739793

Development of automated patch clamp system for electrophysiology

Runhuai Yang
, King W.C. Lai^*
, Ning Xi
, Jie Yang

^*Corresponding author for this work

City University of Hong Kong

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

10 Citations (Scopus)

Abstract

In this paper, the development of an automated patch clamp system for cellular electrical information is reported. The system involves several developments that enable the following tasks: 'pipette and cell localization', 'pipette engaging', 'gigaseal', and 'break-in'. The system enables us to engage the glass micro pipette automatically on the cell membrane, and perform whole cell recording on adherent cells. In a patch clamp experiment, the dynamic changes of resistance of the pipette were monitored, and a successful whole cell recording of a cell was demonstrated. © 2013 IEEE.

Original language	English
Title of host publication	2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013
Publisher	IEEE Computer Society
Pages	2185-2190
DOIs	https://doi.org/10.1109/ROBIO.2013.6739793
Publication status	Published - 2013
Event	2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013 - Shenzhen, China Duration: 12 Dec 2013 → 14 Dec 2013

Conference

Conference	2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013
Place	China
City	Shenzhen
Period	12/12/13 → 14/12/13

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@inproceedings{68e17a7cb4574f1a9e3be670582d0020,

title = "Development of automated patch clamp system for electrophysiology",

abstract = "In this paper, the development of an automated patch clamp system for cellular electrical information is reported. The system involves several developments that enable the following tasks: 'pipette and cell localization', 'pipette engaging', 'gigaseal', and 'break-in'. The system enables us to engage the glass micro pipette automatically on the cell membrane, and perform whole cell recording on adherent cells. In a patch clamp experiment, the dynamic changes of resistance of the pipette were monitored, and a successful whole cell recording of a cell was demonstrated. {\textcopyright} 2013 IEEE.",

author = "Runhuai Yang and Lai, \{King W.C.\} and Ning Xi and Jie Yang",

year = "2013",

doi = "10.1109/ROBIO.2013.6739793",

language = "English",

pages = "2185--2190",

booktitle = "2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013",

publisher = "IEEE Computer Society",

address = "United States",

note = "2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013 ; Conference date: 12-12-2013 Through 14-12-2013",

}

Yang, R, Lai, KWC, Xi, N & Yang, J 2013, Development of automated patch clamp system for electrophysiology. in 2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013., 6739793, IEEE Computer Society, pp. 2185-2190, 2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013, Shenzhen, China, 12/12/13. https://doi.org/10.1109/ROBIO.2013.6739793

Development of automated patch clamp system for electrophysiology. / Yang, Runhuai; Lai, King W.C.; Xi, Ning et al.
2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013. IEEE Computer Society, 2013. p. 2185-2190 6739793.

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

TY - GEN

T1 - Development of automated patch clamp system for electrophysiology

AU - Yang, Runhuai

AU - Lai, King W.C.

AU - Xi, Ning

AU - Yang, Jie

PY - 2013

Y1 - 2013

N2 - In this paper, the development of an automated patch clamp system for cellular electrical information is reported. The system involves several developments that enable the following tasks: 'pipette and cell localization', 'pipette engaging', 'gigaseal', and 'break-in'. The system enables us to engage the glass micro pipette automatically on the cell membrane, and perform whole cell recording on adherent cells. In a patch clamp experiment, the dynamic changes of resistance of the pipette were monitored, and a successful whole cell recording of a cell was demonstrated. © 2013 IEEE.

AB - In this paper, the development of an automated patch clamp system for cellular electrical information is reported. The system involves several developments that enable the following tasks: 'pipette and cell localization', 'pipette engaging', 'gigaseal', and 'break-in'. The system enables us to engage the glass micro pipette automatically on the cell membrane, and perform whole cell recording on adherent cells. In a patch clamp experiment, the dynamic changes of resistance of the pipette were monitored, and a successful whole cell recording of a cell was demonstrated. © 2013 IEEE.

UR - https://www.scopus.com/pages/publications/84898806707

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84898806707&origin=recordpage

U2 - 10.1109/ROBIO.2013.6739793

DO - 10.1109/ROBIO.2013.6739793

M3 - RGC 32 - Refereed conference paper (with host publication)

SP - 2185

EP - 2190

BT - 2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013

PB - IEEE Computer Society

T2 - 2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013

Y2 - 12 December 2013 through 14 December 2013

ER -

Development of automated patch clamp system for electrophysiology

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