Detection of DNA labeled with magnetic nanoparticles using MgO-based magnetic tunnel junction sensors

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • Weifeng Shen
  • Benaiah D. Schrag
  • Matthew J. Carter
  • Jin Xie
  • Shouheng Sun
  • Gang Xiao

Detail(s)

Original languageEnglish
Article number07A306
Journal / PublicationJournal of Applied Physics
Volume103
Issue number7
Online published5 Feb 2008
Publication statusPublished - 1 Apr 2008
Externally publishedYes

Abstract

We have demonstrated the detection of 2.5 μM target DNA labeled with 16 nm Fe3O4 nanoparticles (NPs) and 50 nm commercial MACS™ NPs using arrays of magnetic tunnel junction sensors with (001)-oriented MgO barrier layers. Signal-to-noise ratios of 25 and 12 were obtained with Fe3O4 and MACS™ NPs, respectively. These data show conclusively that MgO-based MTJ sensor arrays are very promising candidates for future applications involving the accurate detection and identification of biomolecules tagged with magnetic nanoparticles. © 2008 American Institute of Physics.

Citation Format(s)

Detection of DNA labeled with magnetic nanoparticles using MgO-based magnetic tunnel junction sensors. / Shen, Weifeng; Schrag, Benaiah D.; Carter, Matthew J. et al.
In: Journal of Applied Physics, Vol. 103, No. 7, 07A306, 01.04.2008.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review