Detecting microRNA from extracellular vesicles for Cardiovascular diseases by using a microfluidic system

Hong-Lin Cheng; Wen-Hsin Chang; Hsing-Yu Lin; Chihchen Chen; Gwo-Bin Lee

Detecting microRNA from extracellular vesicles for Cardiovascular diseases by using a microfluidic system

Hong-Lin Cheng, Wen-Hsin Chang, Hsing-Yu Lin, Chihchen Chen, Gwo-Bin Lee^*

^*Corresponding author for this work

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

Abstract

Cardiovascular diseases (CVDs) are one of major causes of death globally. Circulating microRNAs (miRNAs) mainly exist in exosomes of extracellular vesicles (EV) and could serve as biomarkers for CVDs. Here, we presented a new integrated microfluidic system which is able to perform EV extraction, EV lysis and reverse-transcription polymerase chain reaction (RT-PCR). The entire procedure was automatically performed on an integrated microfluidic chip.

Original language	English
Title of host publication	20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Publisher	Chemical and Biological Microsystems Society
Pages	319-320
ISBN (Print)	9780979806490
Publication status	Published - 2016
Externally published	Yes
Event	20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016) - Dublin, Ireland Duration: 9 Oct 2016 → 13 Oct 2016

Publication series

Name	20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Conference

Conference	20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016)
Place	Ireland
City	Dublin
Period	9/10/16 → 13/10/16

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research Keywords

Cardiovascular diseases
Extracellular vesicles
Microfluidics
MicroRNAs

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Cheng, H.-L., Chang, W.-H., Lin, H.-Y., Chen, C., & Lee, G.-B. (2016). Detecting microRNA from extracellular vesicles for Cardiovascular diseases by using a microfluidic system. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (pp. 319-320). (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016). Chemical and Biological Microsystems Society.

Cheng, Hong-Lin ; Chang, Wen-Hsin ; Lin, Hsing-Yu et al. / Detecting microRNA from extracellular vesicles for Cardiovascular diseases by using a microfluidic system. 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, 2016. pp. 319-320 (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

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title = "Detecting microRNA from extracellular vesicles for Cardiovascular diseases by using a microfluidic system",

abstract = "Cardiovascular diseases (CVDs) are one of major causes of death globally. Circulating microRNAs (miRNAs) mainly exist in exosomes of extracellular vesicles (EV) and could serve as biomarkers for CVDs. Here, we presented a new integrated microfluidic system which is able to perform EV extraction, EV lysis and reverse-transcription polymerase chain reaction (RT-PCR). The entire procedure was automatically performed on an integrated microfluidic chip.",

keywords = "Cardiovascular diseases, Extracellular vesicles, Microfluidics, MicroRNAs",

author = "Hong-Lin Cheng and Wen-Hsin Chang and Hsing-Yu Lin and Chihchen Chen and Gwo-Bin Lee",

note = "Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].; 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016) ; Conference date: 09-10-2016 Through 13-10-2016",

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language = "English",

isbn = "9780979806490",

series = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",

publisher = "Chemical and Biological Microsystems Society",

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booktitle = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",

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Cheng, H-L, Chang, W-H, Lin, H-Y, Chen, C & Lee, G-B 2016, Detecting microRNA from extracellular vesicles for Cardiovascular diseases by using a microfluidic system. in 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, Chemical and Biological Microsystems Society, pp. 319-320, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin, Ireland, 9/10/16.

Detecting microRNA from extracellular vesicles for Cardiovascular diseases by using a microfluidic system. / Cheng, Hong-Lin; Chang, Wen-Hsin; Lin, Hsing-Yu et al.
20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, 2016. p. 319-320 (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

TY - GEN

T1 - Detecting microRNA from extracellular vesicles for Cardiovascular diseases by using a microfluidic system

AU - Cheng, Hong-Lin

AU - Chang, Wen-Hsin

AU - Lin, Hsing-Yu

AU - Chen, Chihchen

AU - Lee, Gwo-Bin

N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

PY - 2016

Y1 - 2016

N2 - Cardiovascular diseases (CVDs) are one of major causes of death globally. Circulating microRNAs (miRNAs) mainly exist in exosomes of extracellular vesicles (EV) and could serve as biomarkers for CVDs. Here, we presented a new integrated microfluidic system which is able to perform EV extraction, EV lysis and reverse-transcription polymerase chain reaction (RT-PCR). The entire procedure was automatically performed on an integrated microfluidic chip.

AB - Cardiovascular diseases (CVDs) are one of major causes of death globally. Circulating microRNAs (miRNAs) mainly exist in exosomes of extracellular vesicles (EV) and could serve as biomarkers for CVDs. Here, we presented a new integrated microfluidic system which is able to perform EV extraction, EV lysis and reverse-transcription polymerase chain reaction (RT-PCR). The entire procedure was automatically performed on an integrated microfluidic chip.

KW - Cardiovascular diseases

KW - Extracellular vesicles

KW - Microfluidics

KW - MicroRNAs

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UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85014238164&origin=recordpage

M3 - RGC 32 - Refereed conference paper (with host publication)

SN - 9780979806490

T3 - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

SP - 319

EP - 320

BT - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

PB - Chemical and Biological Microsystems Society

T2 - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016)

Y2 - 9 October 2016 through 13 October 2016

ER -

Cheng HL, Chang WH, Lin HY, Chen C, Lee GB. Detecting microRNA from extracellular vesicles for Cardiovascular diseases by using a microfluidic system. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society. 2016. p. 319-320. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

Detecting microRNA from extracellular vesicles for Cardiovascular diseases by using a microfluidic system

Abstract

Publication series

Conference

Bibliographical note

UN SDGs

Research Keywords

Other Access Options

Permanent Link

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Cite this