Design and optimization of a chip based on electroelution for the purification and recovery of DNA fragments

A chip based on electroelution principle was presented for the recovery of DNA fragments, which can make the isolation and collection of target DNA fragments possible in a single process by switching electrodes. An optimization design was made for the channel structure and the distribution of the electric field in DNA recovery chip, and experiments were also performed to validate the simulation result. Both theoretical analysis and experimental results show that the optimization design in our existing device can achieve the desired results.