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Depth-first search encoding of RNA substructures

Qingfeng Chen*, Chaowang Lan, Jinyan Li, Baoshan Chen, Lusheng Wang, Chengqi Zhang

*Corresponding author for this work

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review

Abstract

RNA structural motifs are important in RNA folding process. Traditional index-based and shape-based schemas are useful in modeling RNA secondary structures but ignore the structural discrepancy of individual RNA family member. Further, the in-depth analysis of underlying substructure pattern is underdeveloped owing to varied and unnormalized substructures. This prevents us from understanding RNAs functions. This article proposes a DFS (depth-first search) encoding for RNA substructures. The results show that our methods are useful in modelling complex RNA secondary structures.
Original languageEnglish
Title of host publicationIntelligent Computing Theories and Application
Subtitle of host publication12th International Conference, ICIC 2016, Proceedings
EditorsPrashan Premaratne, De-Shuang Huang, Vitoantonio Bevilacqua
PublisherSpringer Verlag
Pages328-334
Volume9771
ISBN (Print)9783319422909
DOIs
Publication statusPublished - 2016
Event12th International Conference on Intelligent Computing Theories and Application, ICIC 2016 - Lanzhou, China
Duration: 2 Aug 20165 Aug 2016

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume9771
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference12th International Conference on Intelligent Computing Theories and Application, ICIC 2016
PlaceChina
CityLanzhou
Period2/08/165/08/16

Research Keywords

  • Data mining
  • RNA
  • Subgraph
  • Substructure
  • Support

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