Cytotoxicity of nanoparticle-loaded polymer capsules

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • C. Kirchner
  • A. Muñoz Javier
  • A. S. Susha
  • O. Kreft
  • G. B. Sukhorukov
  • W. J. Parak

Detail(s)

Original languageEnglish
Pages (from-to)486-491
Journal / PublicationTalanta
Volume67
Issue number3
Publication statusPublished - 15 Sept 2005
Externally publishedYes

Abstract

Cytotoxic effects of micrometer-sized polymer capsules composed out of alternating layers of polystyrenesulfonate (PSS) and polyallylamine hydrochloride (PAH) on a fibroblast cell line have been investigated with an adhesion assay. For the purpose of visualization with fluorescence nanometer-sized CdTe nanoparticles have been embedded in the walls of the capsules. Similar to free CdTe nanoparticles, toxic Cd-ions are also released from CdTe nanoparticles that have been embedded in capsules. At high capsule concentrations, the capsules start to sediment on top of the cells and thus impair cell viability. © 2005 Elsevier B.V. All rights reserved.

Research Area(s)

  • Cytotoxicity, Nanoparticle, Polymer capsule

Citation Format(s)

Cytotoxicity of nanoparticle-loaded polymer capsules. / Kirchner, C.; Javier, A. Muñoz; Susha, A. S. et al.
In: Talanta, Vol. 67, No. 3, 15.09.2005, p. 486-491.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review