Current technological trends in transdermal biosensing

Yuyue Zhang; Cheng Yang; Haibin Shi; Chenjie Xu

doi:10.1002/anbr.202200040

Current technological trends in transdermal biosensing

Yuyue Zhang, Cheng Yang, Haibin Shi, Chenjie Xu^*

^*Corresponding author for this work

Department of Biomedical Engineering

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

15 Citations (Scopus)

93 Downloads (CityUHK Scholars)

Abstract

Transdermal biosensing focuses on the qualitative and quantitative collection and detection of biomarkers on and in the skin layers. In comparison to the blood-based diagnosis, transdermal sensing technologies provide pain-free, convenient, patient-friendly, and infection-avoiding methods to collect biosignals from transdermal samples such as interstitial fluid (ISF) and sweat. This article summarizes the latest trends in transdermal biosensing including the technologies and their application blueprints. Specifically, the current transdermal biosensing technologies including microneedles, microfluidics, and reverse iontophoresis are introduced first. Subsequently, their roles in daily health status monitoring, disease diagnosis and therapy monitoring are discussed in detail. Finally, an overview of the future blueprints and application prospects of transdermal biosensing is provided.

Original language	English
Article number	2200040
Journal	Advanced NanoBiomed Research
Volume	2
Issue number	9
Online published	28 Jun 2022
DOIs	https://doi.org/10.1002/anbr.202200040
Publication status	Published - Sept 2022

Research Keywords

microneedles
skin interstitial fluid
weat
transdermal biosensing
wearable electronics

Publisher's Copyright Statement

This full text is made available under CC-BY 4.0. https://creativecommons.org/licenses/by/4.0/

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10.1002/anbr.202200040

107878568.pdfFinal Published version, 2.63 MBLicence: CC BY

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GRF: Development of Highly Swellable Microneedle Skin Patches for Skin Interstitial Fluid Sampling and In Situ Transdermal Biosensing
XU, C. (Principal Investigator / Project Coordinator) & YU, X. (Co-Investigator)
1/01/21 → 16/12/24
Project: Research
NSFC: Nanometallic Conductive Composite-hydrogel Core-shell Microneedle Skin Patch for Real-time Monitoring Physiological Signals
XU, C. (Principal Investigator / Project Coordinator) & Yang, C. (Co-Investigator)
1/01/21 → 18/02/25
Project: Research

Cite this

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title = "Current technological trends in transdermal biosensing",

abstract = "Transdermal biosensing focuses on the qualitative and quantitative collection and detection of biomarkers on and in the skin layers. In comparison to the blood-based diagnosis, transdermal sensing technologies provide pain-free, convenient, patient-friendly, and infection-avoiding methods to collect biosignals from transdermal samples such as interstitial fluid (ISF) and sweat. This article summarizes the latest trends in transdermal biosensing including the technologies and their application blueprints. Specifically, the current transdermal biosensing technologies including microneedles, microfluidics, and reverse iontophoresis are introduced first. Subsequently, their roles in daily health status monitoring, disease diagnosis and therapy monitoring are discussed in detail. Finally, an overview of the future blueprints and application prospects of transdermal biosensing is provided.",

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doi = "10.1002/anbr.202200040",

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T1 - Current technological trends in transdermal biosensing

AU - Zhang, Yuyue

AU - Yang, Cheng

AU - Shi, Haibin

AU - Xu, Chenjie

PY - 2022/9

Y1 - 2022/9

N2 - Transdermal biosensing focuses on the qualitative and quantitative collection and detection of biomarkers on and in the skin layers. In comparison to the blood-based diagnosis, transdermal sensing technologies provide pain-free, convenient, patient-friendly, and infection-avoiding methods to collect biosignals from transdermal samples such as interstitial fluid (ISF) and sweat. This article summarizes the latest trends in transdermal biosensing including the technologies and their application blueprints. Specifically, the current transdermal biosensing technologies including microneedles, microfluidics, and reverse iontophoresis are introduced first. Subsequently, their roles in daily health status monitoring, disease diagnosis and therapy monitoring are discussed in detail. Finally, an overview of the future blueprints and application prospects of transdermal biosensing is provided.

AB - Transdermal biosensing focuses on the qualitative and quantitative collection and detection of biomarkers on and in the skin layers. In comparison to the blood-based diagnosis, transdermal sensing technologies provide pain-free, convenient, patient-friendly, and infection-avoiding methods to collect biosignals from transdermal samples such as interstitial fluid (ISF) and sweat. This article summarizes the latest trends in transdermal biosensing including the technologies and their application blueprints. Specifically, the current transdermal biosensing technologies including microneedles, microfluidics, and reverse iontophoresis are introduced first. Subsequently, their roles in daily health status monitoring, disease diagnosis and therapy monitoring are discussed in detail. Finally, an overview of the future blueprints and application prospects of transdermal biosensing is provided.

KW - microneedles

KW - skin interstitial fluid

KW - weat

KW - transdermal biosensing

KW - wearable electronics

U2 - 10.1002/anbr.202200040

DO - 10.1002/anbr.202200040

M3 - RGC 21 - Publication in refereed journal

SN - 2699-9307

VL - 2

JO - Advanced NanoBiomed Research

JF - Advanced NanoBiomed Research

IS - 9

M1 - 2200040

ER -

Current technological trends in transdermal biosensing

Abstract

Research Keywords

Publisher's Copyright Statement

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Projects

GRF: Development of Highly Swellable Microneedle Skin Patches for Skin Interstitial Fluid Sampling and In Situ Transdermal Biosensing

NSFC: Nanometallic Conductive Composite-hydrogel Core-shell Microneedle Skin Patch for Real-time Monitoring Physiological Signals

Cite this