Covalent immobilization of oligonucleotides on modified glass/silicon surfaces for solid-phase DNA hybridization and amplification

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Original languageEnglish
Pages (from-to)257-258
Journal / PublicationChemistry Letters
Issue number3
Publication statusPublished - 1998


Glass slides and silicon chips were modified with aminosilane and various linker molecules to provide activated surfaces for covalent immobilization of oligonucleotides under ambient condition, and the surface-attached oligonucleotides remain active for solid-phase DNA hybridization and polymerase chain reaction.