Coumarin-based two-photon AIE fluorophores: Photophysical properties and biological application

Yitong Yang, Hao Zhong, Benhua Wang, Xiaojie Ren*, Xiangzhi Song*

*Corresponding author for this work

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

13 Citations (Scopus)

Abstract

Based on the coumarin skeleton, we deliberately designed two groups of fluorophores, termed as Coum-R and Naph-Coum-R, using the diphenylamino group as the electron donor, which displayed long-wavelength emissions (red spectral region), large Stokes shift (up to 204 nm), superior AIE performance, and large two-photon absorbance cross-sections (as high as 365 GM). The electron-withdrawing substituents at the 3-position of these dyes could induce a significant red-shift in their emission spectra. Preliminary imaging experiments demonstrated the capability of these dyes as two-photon fluorophores for specifically staining lipid droplets in living cells. © 2023 Elsevier B.V.
Original languageEnglish
Article number107674
JournalChinese Chemical Letters
Volume34
Issue number4
Online published12 Jul 2022
DOIs
Publication statusPublished - Apr 2023

Research Keywords

  • AIE
  • Fluorescent dyes
  • Large Stokes shifts
  • Lipid droplets
  • Two-photon

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